关于受体特异性蛋白的观察。II. A、C、D和E型肉毒梭菌血凝素的血凝和血凝抑制反应
Observations on receptor specific proteins. II. Haemagglutination and haemagglutination-inhibition reactions of Clostridium botulinum types A, C, D and E haemagglutinins.
作者信息
Balding P, Gold E R, Boroff D A, Roberts T A
出版信息
Immunology. 1973 Nov;25(5):773-82.
Abstract
The haemagglutinins of types A, C and D have been studied. A haemagglutinin of type E could not be demonstrated. Haemagglutination (H) tests, using normal and enzyme-treated cells, and haemagglutination—inhibition (H/I) tests, with a panel of sugars, amino-acids, sera and other biological substances were performed. The haemagglutinins fall into two distinct categories (i) type A and (ii) types C and D. Whereas type C or D haemagglutinins were only inhibited by certain biological substances, type A haemagglutinin was also weakly inhibited by D-galactose and more strongly by type XIV polysaccharide, which contains D-galactose as a terminal sugar. Types C and D could be distinguished from each other by H and H/I tests.
摘要
已对A、C和D型血凝素进行了研究。未检测到E型血凝素。使用正常细胞和酶处理细胞进行了血凝（H）试验，并使用一组糖类、氨基酸、血清和其他生物物质进行了血凝抑制（H/I）试验。血凝素分为两个不同的类别：（i）A型和（ii）C型和D型。C型或D型血凝素仅被某些生物物质抑制，而A型血凝素也被D-半乳糖微弱抑制，并被含有D-半乳糖作为末端糖的XIV型多糖强烈抑制。C型和D型可通过H试验和H/I试验相互区分。
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