Smilowitz H
J Virol. 1974 Jan;13(1):100-6. doi: 10.1128/JVI.13.1.100-106.1974.
Bacteriophage f1-infected cells are relatively insensitive to a variety of colicins including E1, E2, and K; an f1 gene product is responsible for this insensitivity. A colicin-tolerant mutant cannot grow f1 phage; f1 DNA does not penetrate this mutant properly. One interpretation of these results is that an f1 gene product blocks the penetration of colicins which is necessary for their action, whereas the colicin-tolerant mutation blocks the penetration of colicins as well as phage f1 DNA.
被噬菌体f1感染的细胞对包括E1、E2和K在内的多种大肠杆菌素相对不敏感；一种f1基因产物导致了这种不敏感性。一个耐大肠杆菌素的突变体无法生长f1噬菌体；f1 DNA不能正常穿透这个突变体。对这些结果的一种解释是，一种f1基因产物阻断了大肠杆菌素发挥作用所必需的穿透过程，而耐大肠杆菌素突变则既阻断了大肠杆菌素的穿透，也阻断了噬菌体f1 DNA的穿透。
