Russell S E, Iyer V N
J Bacteriol. 1972 Jul;111(1):7-14. doi: 10.1128/jb.111.1.7-14.1972.
The infection of different Hfr strains of Escherichia coli bearing derepressed R factors of the fi(+) or fi(-) type can result in the loss of the R factor and the conversion of the infected cells to the R(-) state. This extends earlier observations on the elimination of F' factors by bacteriophage M13 infection. Variability in the efficiency of this conversion can arise because of genetic factors independent of the R factor being eliminated. A fraction of the infected but unconverted R(+) cells were M13 carrier strains. The carrier state had an intracellular basis, and single R(+) cells could maintain the carrier state.
带有去阻遏fi(+)或fi(-)型R因子的不同大肠杆菌Hfr菌株感染,可导致R因子丢失,并使受感染细胞转变为R(-)状态。这扩展了早期关于噬菌体M13感染消除F'因子的观察结果。由于与被消除的R因子无关的遗传因素,这种转变效率可能存在差异。一部分受感染但未转变的R(+)细胞是M13携带菌株。携带状态具有细胞内基础,单个R(+)细胞可以维持携带状态。