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由噬菌体M13和M13载体状态所促进的R因子的丢失。

Loss of R factors promoted by bacteriophage M13 and the M13 carrier state.

作者信息

Russell S E, Iyer V N

出版信息

J Bacteriol. 1972 Jul;111(1):7-14. doi: 10.1128/jb.111.1.7-14.1972.

DOI:10.1128/jb.111.1.7-14.1972
PMID:4591485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC251233/
Abstract

The infection of different Hfr strains of Escherichia coli bearing derepressed R factors of the fi(+) or fi(-) type can result in the loss of the R factor and the conversion of the infected cells to the R(-) state. This extends earlier observations on the elimination of F' factors by bacteriophage M13 infection. Variability in the efficiency of this conversion can arise because of genetic factors independent of the R factor being eliminated. A fraction of the infected but unconverted R(+) cells were M13 carrier strains. The carrier state had an intracellular basis, and single R(+) cells could maintain the carrier state.

摘要

带有去阻遏fi(+)或fi(-)型R因子的不同大肠杆菌Hfr菌株感染,可导致R因子丢失,并使受感染细胞转变为R(-)状态。这扩展了早期关于噬菌体M13感染消除F'因子的观察结果。由于与被消除的R因子无关的遗传因素,这种转变效率可能存在差异。一部分受感染但未转变的R(+)细胞是M13携带菌株。携带状态具有细胞内基础,单个R(+)细胞可以维持携带状态。

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本文引用的文献

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Mutants of Escherichia coli requiring methionine or vitamin B12.需要甲硫氨酸或维生素B12的大肠杆菌突变体。
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A proposal for a uniform nomenclature in bacterial genetics.细菌遗传学统一命名法的提议。
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