Silverman J, Chavannes J M, Rigotty J, Ornaf M
Lab Anim Sci. 1979 Apr;29(2):209-13.
Transmissible murine colonic hyperplasia was diagnosed in 6-month-old A/J mice kept under standard laboratory conditions. Bacterial cultures revealed the presence of Citrobacter freundii (4280). Clinical signs included rough coats, feces adhering to the anus, slight dehydration and rectal prolapses. A nonclotting sanquinous intestinal fluid and gross colonic thickening were frequently seen at necropsy. Morbidity was approximately 50%; mortality approximately 25%. Tetracycline appeared to be effective in controlling the disease.
在标准实验室条件下饲养的6月龄A/J小鼠中诊断出可传播性小鼠结肠增生。细菌培养显示存在弗氏柠檬酸杆菌（4280）。临床症状包括被毛粗糙、粪便粘在肛门、轻度脱水和直肠脱垂。尸检时经常发现非凝血性血性肠液和结肠明显增厚。发病率约为50%；死亡率约为25%。四环素似乎对控制该病有效。
