Koerker D J, Ruch W, Chideckel E, Palmer J, Goodner C J, Ensinck J, Gale C C
Science. 1974 Apr 26;184(4135):482-4. doi: 10.1126/science.184.4135.482.
Somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone, inhibits basal insulin secretion in fasted cats and rats. In fasted baboons both basal and arginine-stimulated secretion of insulin and glucagon are inhibited. Somatostatin appears to act directly on the endocrine pancreas. The action is dose-related, rapid in onset, and readily reversed.
生长抑素是一种下丘脑肽，可抑制垂体生长激素的分泌，它能抑制空腹猫和大鼠的基础胰岛素分泌。在空腹狒狒中，基础胰岛素分泌以及精氨酸刺激的胰岛素和胰高血糖素分泌均受到抑制。生长抑素似乎直接作用于内分泌胰腺。其作用与剂量相关，起效迅速，且易于逆转。
