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亚急性感染性心内膜炎的肾脏病变

Renal lesions of subacute infective endocarditis.

作者信息

Boulton-Jones J M, Sissons J G, Evans D J, Peters D K

出版信息

Br Med J. 1974 Apr 6;2(5909):11-4. doi: 10.1136/bmj.2.5909.11.

DOI:10.1136/bmj.2.5909.11
PMID:4595180
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1610141/
Abstract

This paper gives an account of five patients with glomerulonephritis complicating subacute infective endocarditis. In three patients with focal (segmental) glomerulonephritis granular deposits of immunoglobulin and C3 and reduced serum complement suggested an immune-complex aetiology; but in two patients with a diffuse proliferative glomerulonephritis no Ig or C3 was detected in the diseased glomeruli and the pathogenetic mechanism remained undetermined. Four of the five patients developed renal failure needing dialysis.

摘要

本文报道了5例肾小球肾炎并发亚急性感染性心内膜炎的患者。3例局灶性（节段性）肾小球肾炎患者，免疫球蛋白和C3呈颗粒状沉积，血清补体降低，提示病因与免疫复合物有关；但2例弥漫性增生性肾小球肾炎患者，病变肾小球中未检测到免疫球蛋白或C3，发病机制仍未明确。5例患者中有4例出现肾衰竭，需要进行透析治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/cacb8992c113/brmedj01971-0024-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/790711fb32fd/brmedj01971-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/f60625c255c6/brmedj01971-0023-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/9359da20ccfa/brmedj01971-0024-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/4039474d877d/brmedj01971-0024-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/cacb8992c113/brmedj01971-0024-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/790711fb32fd/brmedj01971-0023-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/f60625c255c6/brmedj01971-0023-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/9359da20ccfa/brmedj01971-0024-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/4039474d877d/brmedj01971-0024-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f6/1610141/cacb8992c113/brmedj01971-0024-c.jpg

相似文献

1
Renal lesions of subacute infective endocarditis.亚急性感染性心内膜炎的肾脏病变
Br Med J. 1974 Apr 6;2(5909):11-4. doi: 10.1136/bmj.2.5909.11.
2
Glomerulonephritis with subacute bacterial endocarditis. Immunofluorescent studies.肾小球肾炎合并亚急性细菌性心内膜炎。免疫荧光研究。
Arch Intern Med. 1973 Oct;132(4):578-81.
3
Immune-complex nephritis in bacterial endocarditis.细菌性心内膜炎中的免疫复合物性肾炎。
Arch Intern Med. 1976 Mar;136(3):334-6.
4
Membranoproliferative glomerulonephritis. Localization of early components of complement in glomerular deposits.膜增生性肾小球肾炎。补体早期成分在肾小球沉积物中的定位。
Am J Pathol. 1976 Aug;84(2):283-98.
5
Membraneous glomerulonephritis induced by HB (Australia) antigen-antibody complexes.由HB（澳大利亚）抗原-抗体复合物诱发的膜性肾小球肾炎。
Acta Morphol Acad Sci Hung. 1976;24(1-2):129-38.
6
New insights into the pathogenesis of glomerulonephritis afforded by the study of renal allografts.通过对同种异体肾移植的研究获得的关于肾小球肾炎发病机制的新见解。
Clin Nephrol. 1973 Jan-Feb;1(1):3-7.
7
Immunoglobulin-A distribution in glomerular disease. Analysis of immunofluorescence localization and pathogenetic significance.免疫球蛋白A在肾小球疾病中的分布。免疫荧光定位分析及发病机制意义
Kidney Int. 1973 Jun;3(6):397-408. doi: 10.1038/ki.1973.62.
8
Glomerulitis in typhoid fever.伤寒中的肾小球炎。
Ann Intern Med. 1974 Aug;81(2):210-3. doi: 10.7326/0003-4819-81-2-210.
9
The glomerular complement receptor in immunologically mediated renal glomerular injury.免疫介导的肾小球损伤中的肾小球补体受体
N Engl J Med. 1976 Jul 1;295(1):10-4. doi: 10.1056/NEJM197607012950103.
10
IgE in glomeruli of patients with nephrotic syndrome.肾病综合征患者肾小球中的免疫球蛋白E
Lancet. 1971 May 29;1(7709):1097-9. doi: 10.1016/s0140-6736(71)91838-1.

引用本文的文献

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Subacute Native Valve Infective Endocarditis and Its Multiple Complications.亚急性天然瓣膜感染性心内膜炎及其多种并发症
Case Rep Cardiol. 2020 Jun 23;2020:8826956. doi: 10.1155/2020/8826956. eCollection 2020.
2
Modulatory and regenerative potential of transplanted bone marrow-derived mesenchymal stem cells on rifampicin-induced kidney toxicity.移植的骨髓间充质干细胞对利福平诱导的肾毒性的调节和再生潜力。
Regen Ther. 2018 Sep 25;9:100-110. doi: 10.1016/j.reth.2018.09.001. eCollection 2018 Dec.
3
Two Cases of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody (PR3-ANCA)-related Nephritis in Infectious Endocarditis.

本文引用的文献

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Quantitation of acute and chronic serum sickness in the rabbit.兔急性和慢性血清病的定量分析。
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Immune complex disease. V. The nature of the circulating complexes associated with glomerular alterations in the chronic BSA-rabbit system.免疫复合物疾病。五、慢性牛血清白蛋白-兔系统中与肾小球改变相关的循环复合物的性质。
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Immune complexes in human diseases: a review.人类疾病中的免疫复合物：综述
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Self-induced glomerulonephritis.自身免疫性肾小球肾炎
Br Med J. 1974 Aug 10;3(5927):387-90. doi: 10.1136/bmj.3.5927.387.
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Morbidity and mortality after peritoneovenous shunt surgery for refractory ascites.顽固性腹水行腹腔静脉分流术后的发病率和死亡率。
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Circulating immune complexes associated with decreased complement-mediated inhibition of immune precipitation in sera from patients with bacterial endocarditis.循环免疫复合物与细菌性心内膜炎患者血清中补体介导的免疫沉淀抑制作用降低有关。
Clin Exp Immunol. 1986 Feb;63(2):359-66.
10
The aetiology and pathogenesis of major systemic vasculitides.主要系统性血管炎的病因及发病机制。
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Progressive Coxsackie viral pancarditis and nephritis.进行性柯萨奇病毒性全心炎和肾炎。
Ann Intern Med. 1969 Nov;71(5):963-70. doi: 10.7326/0003-4819-71-5-963.
5
Glomerulonephritis, nephrotic syndrome and bacterial endocarditis.肾小球肾炎、肾病综合征和细菌性心内膜炎。
S Afr Med J. 1972 Jun 17;46(25):850-1.
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Kidney in subacute endocarditis. Pathological and immunofluorescence findings.亚急性心内膜炎中的肾脏。病理及免疫荧光检查结果。
Arch Pathol. 1972 Sep;94(3):205-13.
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The immune complex glomerulonephritis of bacterial endocarditis.细菌性心内膜炎的免疫复合物性肾小球肾炎
Medicine (Baltimore). 1972 Jan;51(1):1-25. doi: 10.1097/00005792-197201000-00001.
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Acute diffuse glomerulonephritis in acute staphylococcal endocarditis.急性葡萄球菌性心内膜炎中的急性弥漫性肾小球肾炎。
Ann Intern Med. 1969 Aug;71(2):335-41. doi: 10.7326/0003-4819-71-2-335.
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The immune nature of subacute bacterial endocarditis (SBE) nephritis.亚急性细菌性心内膜炎（SBE）肾炎的免疫特性。
Am J Med. 1973 May;54(5):645-52. doi: 10.1016/0002-9343(73)90123-x.
10
Role of C3b in the breakdown of C3 in hypocomplementaemic mesangiocapillary glomerulonephritis.C3b在低补体血症性系膜毛细血管性肾小球肾炎中C3分解代谢中的作用
Lancet. 1973 Mar 3;1(7801):447-9. doi: 10.1016/s0140-6736(73)91877-1.