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子痫前期患者凝血与纤溶功能的评估

Assessment of coagulation and fibrinolysis in pre-eclampsia.

作者信息

Wood S M, Burnett D, Picken A M, Farrell G W, Wolf P

出版信息

Br Med J. 1974 Apr 20;2(5911):145-9. doi: 10.1136/bmj.2.5911.145.

Abstract

A method is described for distinguishing coagulation from fibrinolysis by three estimates of fibrinogen. This "fibrinogen series" together with plasma antithrombin and urinary urokinase have been compared in pregnant patients with venous thrombosis and pre-eclampsia. Evidence is presented for active coagulation during deterioration of the pre-eclampsia state and for enhanced fibrinolysis during improvement.

摘要

本文描述了一种通过对纤维蛋白原进行三次评估来区分凝血与纤维蛋白溶解的方法。已将这种“纤维蛋白原系列”以及血浆抗凝血酶和尿激酶在患有静脉血栓形成和先兆子痫的孕妇中进行了比较。文中提供了证据,表明先兆子痫状态恶化时存在活跃凝血,而病情改善时纤维蛋白溶解增强。

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本文引用的文献

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On the pathogenesis of pre-eclampsia and eclampsia.论子痫前期和子痫的发病机制。
J Obstet Gynaecol Br Commonw. 1972 Oct;79(10):883-94. doi: 10.1111/j.1471-0528.1972.tb12184.x.

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