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1
Fibrin degradation products in pre-eclamptic toxaemia and eclampsia.先兆子痫和子痫中的纤维蛋白降解产物
Br Med J. 1970 Sep 5;3(5722):545-7. doi: 10.1136/bmj.3.5722.545.
2
Intravascular coagulation and abnormal lung-scans in pre-eclampsia and eclampsia. The birmingham Eclampsia Study Group.
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3
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4
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5
Soluble fibrinogen/fibrin complexes in pre-eclampsia.
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6
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7
Coagulation and fibrinolytic systems in pre-eclampsia and eclampsia.子痫前期和子痫中的凝血与纤溶系统。
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8
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Abnormal hemostasis and coagulopathy in preeclampsia and eclampsia.
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10
Abnormal coagulation and fibrinolysis in eclampsia. A clinical and laboratory correlation study.
Am J Obstet Gynecol. 1976 Apr 1;124(7):681-7. doi: 10.1016/s0002-9378(16)33335-x.

引用本文的文献

1
Laboratory findings in hypertensive disorders of pregnancy.妊娠期高血压疾病的实验室检查结果
J Natl Med Assoc. 1996 Dec;88(12):794-8.
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Coagulation and fibrinolytic systems in pre-eclampsia and eclampsia.子痫前期和子痫中的凝血与纤溶系统。
Br Med J. 1971 Apr 3;2(5752):12-6. doi: 10.1136/bmj.2.5752.12.
3
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Br Med J. 1974 Mar 16;1(5906):468-9.
4
Assessment of coagulation and fibrinolysis in pre-eclampsia.子痫前期患者凝血与纤溶功能的评估
Br Med J. 1974 Apr 20;2(5911):145-9. doi: 10.1136/bmj.2.5911.145.
5
The histology of eclamptic lesions.子痫病变的组织学
J Clin Pathol Suppl (R Coll Pathol). 1976;10:63-9.
6
Coagulation and fibrinolysis in intact hydatidiform molar pregnancy.完全性葡萄胎妊娠中的凝血与纤溶
Br Med J. 1976 Dec 18;2(6050):1481-4. doi: 10.1136/bmj.2.6050.1481.
7
Conditions for collection of serum samples for the measurement of fibrin(ogen) degradation products by radioimmunoassay of fragment E.通过片段E放射免疫测定法测量纤维蛋白（原）降解产物时血清样本的采集条件。
J Clin Pathol. 1976 Apr;29(4):336-40. doi: 10.1136/jcp.29.4.336.
8
[Pathogenesis of uremic pneumonitis (author's transl)].
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Early platelet consumption in pre-eclampsia.子痫前期的早期血小板消耗
Br Med J. 1978 Feb 25;1(6111):467-9. doi: 10.1136/bmj.1.6111.467.
10
Coagulation problems in human pregnancy.人类妊娠中的凝血问题。
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本文引用的文献

1
Increased clotting factors in pregnancy.孕期凝血因子增加。
N Engl J Med. 1961 Nov 30;265:1093-7. doi: 10.1056/NEJM196111302652205.
2
INTRAVASCULAR COAGULATION, THE SHWARTZMAN REACTION AND THE PATHOGENESIS OF T.T.P.血管内凝血、施瓦茨曼反应与血栓性血小板减少性紫癜的发病机制
Blood. 1964 Dec;24:775-9.
3
IMMUNOFLUORESCENT STUDIES OF RENAL BIOPSIES IN THE DIAGNOSIS OF TOXEMIA OF PREGNANCY.肾活检免疫荧光研究在妊娠中毒症诊断中的应用
Obstet Gynecol. 1964 Jul;24:32-46.
4
NORMAL VALUES OF CERTAIN FACTORS IN THE BLOOD CLOTTING MECHANISM IN PREGNANCY.孕期血液凝固机制中某些因子的正常值
Am J Obstet Gynecol. 1964 Sep 1;90:44-50. doi: 10.1016/s0002-9378(16)34890-6.
5
THE PATHOGENIC ROLE OF FIBRIN DEPOSITION IN THE GLOMERULAR LESIONS OF TOXEMIA OF PREGNANCY.纤维蛋白沉积在妊娠中毒症肾小球病变中的致病作用。
J Exp Med. 1963 Sep 1;118(3):467-78. doi: 10.1084/jem.118.3.467.
6
Microangiopathic haemolytic anaemia: the possible role of vascular lesions in pathogenesis.微血管病性溶血性贫血：血管病变在发病机制中的可能作用。
Br J Haematol. 1962 Oct;8:358-74. doi: 10.1111/j.1365-2141.1962.tb06541.x.
7
The pathogenesis of eclamptic lesions.子痫病变的发病机制。
Pathol Microbiol (Basel). 1961;24:561-75. doi: 10.1159/000161165.
8
Fibrinolysis in normal pregnancy.正常妊娠中的纤维蛋白溶解
J Clin Pathol. 1958 Jul;11(4):306-10. doi: 10.1136/jcp.11.4.306.
9
Alterations in the blood coagulation system induced by bacterial endotoxin. I. In vivo (generalized Shwartzman reaction).细菌内毒素引起的血液凝固系统改变。I. 体内（全身性施瓦茨曼反应）
J Exp Med. 1958 Mar 1;107(3):353-67. doi: 10.1084/jem.107.3.353.
10
The biological significance of fibrinolysis.纤维蛋白溶解的生物学意义。
Lancet. 1956 Sep 15;271(6942):565-8. doi: 10.1016/s0140-6736(56)92048-7.

先兆子痫和子痫中的纤维蛋白降解产物

Fibrin degradation products in pre-eclamptic toxaemia and eclampsia.

作者信息

Henderson A H, Pugsley D J, Thomas D P

出版信息

Br Med J. 1970 Sep 5;3(5722):545-7. doi: 10.1136/bmj.3.5722.545.

DOI:10.1136/bmj.3.5722.545
PMID:5454355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1701571/
Abstract

Serum levels of fibrinogen/fibrin degradation products, measured in African women, were significantly higher in pre-eclamptic toxaemia than in normal pregnancy, and were significantly higher with eclampsia than with toxaemia. These findings are in accord with the hypothesis that eclampsia and toxaemia are associated with disseminated intravascular coagulation, which may be responsible for certain clinical manifestations of these conditions.

摘要

在非洲女性中检测的血清纤维蛋白原/纤维蛋白降解产物水平，先兆子痫患者显著高于正常妊娠者，子痫患者显著高于先兆子痫患者。这些发现符合以下假说：子痫和先兆子痫与弥散性血管内凝血有关，而弥散性血管内凝血可能是这些病症某些临床表现的原因。