泰国健康成年人中的耐药性大肠杆菌和克雷伯菌属-肠杆菌属以及抗生素给药的影响。
Drug-resistant Escherichia coli and Klebsiella-Enterobacter in healthy adults in Thailand and the effect of antibiotic administration.
作者信息
Koonkhamlert C, Sawyer W D
出版信息
Antimicrob Agents Chemother. 1973 Aug;4(2):198-200. doi: 10.1128/AAC.4.2.198.
Abstract
Antibiotic-resistant strains of Escherichia coli and, to a lesser extent, Klebsiella-Enterobacter were common in serial samples of the normal intestinal flora of healthy young adults in Thailand, and the resistance often was to multiple drugs and was transferable. Antibiotic administration promoted dominance of the flora by drug-resistant organisms regardless of the drug regimen and the predrug susceptibility pattern of the flora. The normal pattern was regained slowly after the cessation of drug administration.
摘要
在泰国健康年轻成年人正常肠道菌群的系列样本中，耐抗生素的大肠杆菌菌株以及程度稍轻的克雷伯菌-肠杆菌属菌株很常见，且这种耐药性往往是多重耐药，并且可转移。无论用药方案以及菌群用药前的药敏模式如何，抗生素给药都会促使耐药菌在菌群中占据主导地位。停药后，正常模式会缓慢恢复。
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