伦敦患者入院前后肠道细菌中的耐药性与R因子
Drug resistance and R factors in the bowel bacteria of London patients before and after admission to hospital.
作者信息
Datta N
出版信息
Br Med J. 1969 May 17;2(5654):407-11. doi: 10.1136/bmj.2.5654.407.
Abstract
The content of drug-resistant coliform bacteria in faecal specimens collected before admission from patients awaiting non-urgent surgery were compared with specimens collected in hospital. Resistant strains of Escherichia coli were isolated from 52% of preadmission specimens and were present in large numbers in 28%. Tetracycline, sulphonamide, and streptomycin resistance were commonest: 60% of resistant strains carried transmissible R factors and multiple resistance was commoner than single. No characteristically resistant intestinal bacteria of any genera were found in hospital specimens as compared with those from outside.
摘要
将等待非紧急手术患者入院前采集的粪便标本中耐药性大肠菌的含量与住院期间采集的标本进行了比较。从52%的入院前标本中分离出了大肠杆菌耐药菌株，其中28%的标本中耐药菌株数量众多。四环素、磺胺和链霉素耐药最为常见：60%的耐药菌株携带可传递的R因子，多重耐药比单一耐药更为常见。与院外标本相比，在住院标本中未发现任何属的具有特征性耐药的肠道细菌。
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