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与DNA结合相关的T4早期蛋白质的协同相互作用。

Synergistic interactions of T4 early proteins concerned with their binding to DNA.

作者信息

Huang W M, Buchanan J M

出版信息

Proc Natl Acad Sci U S A. 1974 Jun;71(6):2226-30. doi: 10.1073/pnas.71.6.2226.

DOI:10.1073/pnas.71.6.2226
PMID:4601582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC388424/
Abstract

Under appropriate conditions, 19 distinct early proteins produced by bacteriophage T4 bind DNA with various affinities. They include products of genes that have been implicated in T4 DNA metabolism, such as DNA negative, DNA arrest, and DNA delay genes, and others whose roles have not yet been defined. The identifiable DNA-binding proteins are the products of genes 43, rIIA, 46, 30, 39, 52, betagt, 32, and internal protein III. In some cases, protein-protein interactions are involved in the formation of the DNA-protein complexes.

摘要

在适当条件下,噬菌体T4产生的19种不同的早期蛋白质以不同亲和力结合DNA。它们包括与T4 DNA代谢相关的基因产物,如DNA阴性、DNA停滞和DNA延迟基因,以及其他作用尚未明确的基因产物。可识别的DNA结合蛋白是基因43、rIIA、46、30、39、52、betagt、32和内部蛋白III的产物。在某些情况下,蛋白质-蛋白质相互作用参与了DNA-蛋白质复合物的形成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/1b48fe2ab1d3/pnas00059-0079-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/486c68cacbaf/pnas00059-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/c4d2422b20bb/pnas00059-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/f7f4c8af20b6/pnas00059-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/731fe461b4d2/pnas00059-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/9375afc81480/pnas00059-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/1b48fe2ab1d3/pnas00059-0079-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/486c68cacbaf/pnas00059-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/c4d2422b20bb/pnas00059-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/f7f4c8af20b6/pnas00059-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/731fe461b4d2/pnas00059-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/9375afc81480/pnas00059-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ba/388424/1b48fe2ab1d3/pnas00059-0079-c.jpg

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本文引用的文献

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TEMPERATURE-SENSITIVE MUTANTS OF BACTERIOPHAGE T4D: THEIR ISOLATION AND GENETIC CHARACTERIZATION.噬菌体T4D的温度敏感突变体:其分离与遗传特性
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