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美丽新世界?

Brave new world?

作者信息

Motulsky A G

出版信息

Science. 1974 Aug;185(4152):653-63. doi: 10.1126/science.185.4152.653.

DOI:10.1126/science.185.4152.653
PMID:4601914
Abstract

Recent developments in biology and medicine are raising new problems in the prevention and treatment of birth defects, and in research on these diseases. The problems include immediate issues such as genetic counseling, abortion for birth defects, the withholding of complex treatments from individuals in some situations, screening for genetic and other diseases, artificial insemination, and fertilization in vitro. Other problems, such as the dysgenic effects of modern medicine and the possibilities of cloning and gene therapy, are more remote. Each of these issues should be considered on its own merits and by its immediate and remote consequences rather than by a priori absolute criteria. Ways must be found to deal with these issues in a manner acceptable to most human beings. Open discussions and freedom from coercion are the best guarantees for ultimate success. The ethical human brain is the highest accomplishment of biologic evolution. By harmonizing our scientific, cultural, and ethical capabilities, the potentially achievable results can place us at the threshold of a new era of better health and less human suffering.

摘要

生物学和医学领域的最新进展在出生缺陷的预防与治疗以及这些疾病的研究方面引发了新问题。这些问题包括诸如遗传咨询、因出生缺陷而堕胎、在某些情况下对个体停止复杂治疗、遗传及其他疾病的筛查、人工授精和体外受精等紧迫问题。其他问题,如现代医学的不良遗传影响以及克隆和基因治疗的可能性,则较为遥远。这些问题中的每一个都应根据其自身的优缺点以及直接和间接后果来考虑,而不是依据先验的绝对标准。必须找到以大多数人可接受的方式处理这些问题的方法。公开讨论和免受强制是最终成功的最佳保障。有道德的人类大脑是生物进化的最高成就。通过协调我们的科学、文化和道德能力,潜在可实现的成果能够使我们站在一个健康状况更佳、人类痛苦更少的新时代的门槛上。

相似文献

1
Brave new world?美丽新世界?
Science. 1974 Aug;185(4152):653-63. doi: 10.1126/science.185.4152.653.
2
Early diagnosis and prevention of genetic disease.遗传疾病的早期诊断与预防。
Ann Clin Biochem. 1979 Nov;16(6):343-53. doi: 10.1177/000456327901600192.
3
Practical and ethical problems in human genetics.人类遗传学中的实际问题与伦理问题。
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4
[Disputed problems in perinatal medicine].[围产期医学中的争议问题]
Akush Ginekol (Mosk). 1989 Sep(9):3-7.
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Genetic disorders.遗传性疾病
Clin Obstet Gynaecol. 1982 Apr;9(1):3-27.
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[Perspectives in medical genetics].
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[Ethical aspects of modern genetics].[现代遗传学的伦理问题]
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Societal problems in human and medical genetics.人类与医学遗传学中的社会问题。
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Recent developments in the prenatal diagnosis of genetic diseases and birth defects.遗传疾病和出生缺陷产前诊断的最新进展。
Annu Rev Genet. 1983;17:49-83. doi: 10.1146/annurev.ge.17.120183.000405.
10
Prenatal diagnosis of hereditary disease and congenital defects.
Pediatr Ann. 1981 Feb;10(2):22-37.

引用本文的文献

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Modular Ontologies for Genetically Modified People and their Bioethical Implications.转基因人类的模块化本体及其生物伦理意义。
Nanoethics. 2024;18(2):9. doi: 10.1007/s11569-024-00459-4. Epub 2024 Aug 19.
2
Perception, experience, and response to genetic discrimination in Huntington's disease: the Australian results of The International RESPOND-HD study.亨廷顿舞蹈症患者对基因歧视的认知、经历及反应:国际 RESPOND-HD 研究的澳大利亚结果
Genet Test Mol Biomarkers. 2013 Feb;17(2):115-21. doi: 10.1089/gtmb.2012.0288. Epub 2013 Jan 4.
3
Prevention of homozygous beta-thalassemia by carrier screening and prenatal diagnosis in Sardinia.
通过在撒丁岛进行携带者筛查和产前诊断预防纯合子β地中海贫血。
Am J Hum Genet. 1981 Jul;33(4):592-605.
4
Policy choices available in genetic counseling for people at-risk for Huntington's disease.
Psychiatr Q. 1981 Fall;53(3):194-200. doi: 10.1007/BF01064990.
5
Discrimination as a consequence of genetic testing.基因检测导致的歧视。
Am J Hum Genet. 1992 Mar;50(3):476-82.
6
Screening and genetic counseling for beta-thalassemia trait in a population unselected for interest: effects on knowledge and mood.对未因感兴趣而被选择的人群进行β地中海贫血特征的筛查和遗传咨询:对知识和情绪的影响。
Am J Hum Genet. 1979 Nov;31(6):718-30.