Crew A D, Varkonyi P I, Gardner L G, Robinson Q L, Wall E, Deverall P B
Thorax. 1974 Jul;29(4):437-45. doi: 10.1136/thx.29.4.437.
, , 437-445. Continuous positive airway pressure with spontaneous ventilation was used in the postoperative period following palliative or corrective surgery for congenital heart defects in a group of children of less than 3 years of age. After stabilization of the cardiovascular state, continuous positive airway pressure breathing (CPAP) was shown to be a suitable alternative to continuous positive pressure ventilation (CPPV). A statistically significant increase in PaO was observed on changing from CPPV to CPAP. A statistically significant decrease in PaO and increase in pulmonary venous admixture was observed after discontinuing the positive airway pressure and allowing the patient to breathe at ambient pressure. We would recommend CPAP as an intermediate manoeuvre in the withdrawal of ventilatory support as it introduces a smoothness and stability into patient management régimes which was previously lacking. Careful selection of apparatus is necessary as the airway pressure should be truly continuous and steady. In neonates the dead space of the system should be reduced to a minimum; CPAP alternating with periods on CPPV may be necessary for some time after cardiovascular stability has been attained.
在一组3岁以下接受先天性心脏缺陷姑息性或矫正性手术后的儿童术后阶段,采用持续气道正压通气与自主通气相结合的方式。在心血管状态稳定后,持续气道正压通气(CPAP)被证明是持续正压通气(CPPV)的合适替代方法。从CPPV转换为CPAP时,观察到动脉血氧分压(PaO)有统计学意义的升高。在停止气道正压通气并让患者在常压下呼吸后,观察到PaO有统计学意义的下降以及肺静脉混合血增加。我们建议将CPAP作为撤机支持的中间操作,因为它为患者管理模式引入了以前所缺乏的平稳性和稳定性。由于气道压力应真正持续且稳定,因此必须仔细选择设备。对于新生儿,系统的死腔应减至最小;在心血管稳定后一段时间内,可能需要CPAP与CPPV阶段交替使用。