Cogswell J J, Hatch D J, Kerr A A, Taylor B
Arch Dis Child. 1975 Oct;50(10):799-804. doi: 10.1136/adc.50.10.799.
The effect of continuous positive airway pressure (CPAP) on lung mechanics was investigated in 12 babies after operation for severe congenital heart disease. At the time of study all babies were receiving or being weaned from ventilatory support and had abnormally low lung volume or compliance. During CPAP there was a fall in the pulmonary resistance which, with a slight decrease in minute ventilation, resulted in a significant decrease in the work of breathing. It is suggested that lowering the oxygen cost of breathing may contribute to the improvement in arterial oxygenation seen when CPAP is used.
对12名重症先天性心脏病术后婴儿进行了持续气道正压通气(CPAP)对肺力学影响的研究。在研究时,所有婴儿均接受通气支持或正在撤机,且肺容量或顺应性异常低。在CPAP治疗期间,肺阻力下降,同时分钟通气量略有减少,导致呼吸功显著降低。有人认为,降低呼吸的氧消耗可能有助于解释使用CPAP时动脉氧合的改善。