肾移植患者对流感疫苗的反应。
Response to influenza vaccine by renal transplant patients.
作者信息
Carroll R N, Marsh S D, O'Donoghue E P, Breeze D C, Shackman R
出版信息
Br Med J. 1974 Jun 29;2(5921):701-3. doi: 10.1136/bmj.2.5921.701.
Abstract
Twenty-five renal transplant patients and 17 controls were vaccinated with influenza vaccine. Antibody titres were estimated before and one, three, and 12 months after vaccination. On the basis of antibody titre measurements the transplant group showed a similar qualitative and quantitative response to that of the controls. No rejection episodes occurred among the transplant patients as a result of vaccination and nobody in the trial developed influenza. We conclude that it is safe to vaccinate transplant patients with an inactivated influenza vaccine and that protection (haemagglutination-inhibiting antibody) can be induced.
摘要
25名肾移植患者和17名对照者接种了流感疫苗。在接种疫苗前以及接种后1个月、3个月和12个月时对抗体滴度进行了评估。根据抗体滴度测量结果，移植组在定性和定量反应方面与对照组相似。接种疫苗后，移植患者中未发生排斥反应，且试验中无人感染流感。我们得出结论，给移植患者接种灭活流感疫苗是安全的，并且可以诱导产生保护作用（血凝抑制抗体）。
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本文引用的文献
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Viral infection and renal transplant rejection.病毒感染与肾移植排斥反应。
Br Med J. 1972 Dec 2;4(5839):520-2. doi: 10.1136/bmj.4.5839.520.
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Viral syndromes and renal homograft rejection.病毒综合征与同种异体肾移植排斥反应
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