胰酶肠溶胶囊V强效片与营养酶治疗囊性纤维化吸收不良的对比试验。
Comparative trial of pancrex V forte and nutrizym in treatment of malabsorption in cystic fibrosis.
作者信息
Goodchild M C, Sagaró E, Brown G A, Cruchley P M, Jukes H R, Anderson C M
出版信息
Br Med J. 1974 Sep 21;3(5933):712-4. doi: 10.1136/bmj.3.5933.712.
Abstract
A cross-over trial of pancreatic enzyme replacement therapy has been conducted on 12 children with cystic fibrosis using Pancrex V forte and Nutrizym tablets in equivalent dosage. No differences were found in the effectiveness of these products as measured by stool volume, number of bowel actions, faecal fat excretion, and urine urea excretion. Neither product eliminated the steatorrhoea. Though there was no laboratory evidence to support their choice nine patients expressed a preference for Nutrizym at the conclusion of the trial. This preference was based partly on the smaller number of tablets which are required.
摘要
一项针对12名囊性纤维化儿童的胰腺酶替代疗法交叉试验，使用了等效剂量的V forte胰酶片和Nutrizym片。通过粪便体积、排便次数、粪便脂肪排泄和尿尿素排泄来衡量，这些产品的有效性没有差异。两种产品均未消除脂肪泻。尽管没有实验室证据支持他们的选择，但9名患者在试验结束时表示更喜欢Nutrizym。这种偏好部分基于所需片剂数量较少。
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本文引用的文献
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