D-葡萄糖异头物的胰岛素分泌
Insulin secretion by anomers of d-glucose.
作者信息
Niki A, Niki H, Miwa I, Okuda J
出版信息
Science. 1974 Oct 11;186(4159):150-1. doi: 10.1126/science.186.4159.150.
PMID:4606675
Abstract
Isolated rat islets were incubated for 5 minutes in the media containing either the alpha or beta anomer of D-glucose (2 milligrams per milliliter). The amounts of secreted insulin and changes of anomers ratio were concomitantly determined. In spite of rapid mutarotation, significantly greater stimulation of insulin secretion was observed by alpha-D-glucose as compared with beta-D-glucose.
摘要
将分离出的大鼠胰岛在含有α-D-葡萄糖或β-D-葡萄糖（2毫克/毫升）的培养基中孵育5分钟。同时测定胰岛素分泌量和异头物比例的变化。尽管存在快速的变旋现象，但与β-D-葡萄糖相比，α-D-葡萄糖对胰岛素分泌的刺激作用明显更强。
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