与辐射诱导的DNA降解的诱导性抑制剂相关的辐射诱导链断裂的修复
Repair of radiation-induced strand breaks as related to the inducible inhibitor of postirradiation DNA degradation.
作者信息
Tolun A, Christensen R, Pollard E C
出版信息
Biophys J. 1974 Sep;14(9):691-6. doi: 10.1016/S0006-3495(74)85944-8.
Abstract
The repair of radiation-produced single-strand breaks observed under alkaline conditions is very apparent in cells which possess an inducible inhibitor of postirradiation DNA degradation. Previous induction of the inhibitor with ultraviolet light increases the amount of repair. In those cells which are genetically not inducible there is no increase following ultraviolet irradiation.
摘要
在碱性条件下观察到的辐射产生的单链断裂修复，在具有辐射后DNA降解诱导抑制剂的细胞中非常明显。先前用紫外线诱导该抑制剂会增加修复量。在那些基因上不可诱导的细胞中，紫外线照射后没有增加。
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