依赖胸苷的大肠杆菌感染及一些相关的实验室问题。
Thymidine-dependent Escherichia coli infection and some associated laboratory problems.
作者信息
Tanner E I, Bullin C H
出版信息
J Clin Pathol. 1974 Jul;27(7):565-8. doi: 10.1136/jcp.27.7.565.
Abstract
The rapid emergence of a thymidine-dependent strain of Escherichia coli in a patient treated with co-trimoxazole is described. The organism was recovered from blood cultures during a septicaemia which developed after only a few days of co-trimoxazole treatment. The cultural characteristics of three thymidine-dependent strains were studied and a remarkable variation was found in their ability to grow on different batches of blood agar, depending upon the age of the plates and the type of agar base used.
摘要
本文描述了在一名接受复方新诺明治疗的患者中迅速出现的一株依赖胸苷的大肠杆菌。该菌株是在复方新诺明治疗仅几天后发生败血症期间从血培养物中分离出来的。研究了三株依赖胸苷菌株的培养特性，发现它们在不同批次血琼脂上的生长能力存在显著差异，这取决于平板的保存时间和所用琼脂基础的类型。
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本文引用的文献
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Reversal of the antimicrobial activity of trimethoprim by thymidine in commercially prepared media.在商业制备的培养基中，胸腺嘧啶核苷可逆转甲氧苄啶的抗菌活性。
Appl Microbiol. 1971 Nov;22(5):812-7. doi: 10.1128/am.22.5.812-817.1971.
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Thymine-requiring mutants of Proteus mirabilis selected by co-trimoxazole in vivo.
J Gen Microbiol. 1973 Aug;77(2):533-5. doi: 10.1099/00221287-77-2-533.
3
Characteristics of some co-trimoxazole-resistant Enterobacteriaceae from infected patients.感染患者中部分耐复方新诺明肠杆菌科细菌的特征。
J Clin Pathol. 1972 Dec;25(12):1086-8. doi: 10.1136/jcp.25.12.1086.
4
Joint trimethoprim and sulphamethoxazole resistance in bacteria infected with R factors.感染R因子的细菌对甲氧苄啶和磺胺甲恶唑的联合耐药性。
J Med Microbiol. 1973 Feb;6(1):13-9. doi: 10.1099/00222615-6-1-13.
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Sensitivity testing with trimethorpim-sulphamethoxazole.用甲氧苄啶-磺胺甲恶唑进行敏感性测试。
Med J Aust. 1973 Jun 30;1(2):Suppl:10-8.
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