Cattell W R, McSherry M A, Northeast A, Powell E, Brooks H J, O'Grady F
Br Med J. 1974 Oct 19;4(5937):136-9. doi: 10.1136/bmj.4.5937.136.
Periurethral carriage rates of enterobacteria have been studied in 20 normal women, 34 patients between episodes of bacteriuria, 34 patients with the "urethral syndrome," and 15 asymptomatic abacteriuric patients with a previous history of frequency and dysuria.Over a six-week period no difference in the Escherichia coli carriage rate was shown between these four groups. The carriage of all enterobacteria was slightly but significantly (P <0.05) lower in normal women compared with the patient groups but no difference was observed between the latter. There was no difference in the recovery rate and carriage of individual E. coli serotypes between the four groups.It is concluded that the presence of enterobacteria or E. coli on the periurethral area is not the principal determinant factor in the pathogenesis of recurrent urinary tract infection or the urethral syndrome and that definition of carriage status is of little practical value in management.
研究了20名正常女性、34名菌尿症发作间期患者、34名患有“尿道综合征”的患者以及15名有尿频和排尿困难既往史的无症状无菌尿患者的尿道周围肠杆菌携带率。在六周的时间里，这四组之间未显示出大肠杆菌携带率的差异。与患者组相比，正常女性中所有肠杆菌的携带率略低但具有显著差异（P<0.05），但患者组之间未观察到差异。四组之间在单个大肠杆菌血清型的回收率和携带率方面没有差异。得出的结论是，尿道周围区域存在肠杆菌或大肠杆菌不是复发性尿路感染或尿道综合征发病机制的主要决定因素，并且携带状态的定义在管理中几乎没有实际价值。
