牛分枝杆菌和鸟分枝杆菌感染牛中巨噬细胞依赖性淋巴细胞免疫刺激
Macrophage-dependent lymphocyte immunostimulation in cattle infected with Mycobacterium bovis and with Mycobacterium avium.
作者信息
Muscoplat C C, Thoen C O, Chen A W, Johnson D W
出版信息
Infect Immun. 1974 Sep;10(3):675-7. doi: 10.1128/iai.10.3.675-677.1974.
Abstract
Cultures of bovine peripheral blood leukocytes were prepared from calves inoculated with Mycobacterium bovis and with M. avium. Suitable lymphocyte stimulation was obtained with specific and nonspecific mycobacterial mitogens. Leukocyte cultures depleted of adherent, macrophage-type cells did not respond to stimulation with purified protein derivative, although they were responsive to phytohemagglutinin.
摘要
从接种了牛分枝杆菌和鸟分枝杆菌的小牛制备牛外周血白细胞培养物。用特异性和非特异性分枝杆菌促细胞分裂剂可获得合适的淋巴细胞刺激。去除贴壁的巨噬细胞型细胞的白细胞培养物对纯化蛋白衍生物的刺激无反应，尽管它们对植物血凝素敏感。
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