Baine W B, Koenig M G, Goodman J S
Infect Immun. 1974 Dec;10(6):1420-5. doi: 10.1128/iai.10.6.1420-1425.1974.
Candida albicans injected intravenously into rabbits were rapidly cleared from the bloodstream. Organisms injected into a peripheral vein were predominantly cleared by the lungs; organisms injected into a mesenteric vein were largely cleared by the liver. The isolated, perfused rabbit liver avidly cleared candida organisms from buffer perfusate, but clearance was enhanced when the organisms were suspended in heated normal rabbit serum and was most complete when fresh normal rabbit serum was used as the perfusate.
静脉注射到兔子体内的白色念珠菌会迅速从血液中清除。注入外周静脉的微生物主要被肺部清除；注入肠系膜静脉的微生物大部分被肝脏清除。分离并灌注的兔肝能从缓冲液灌注液中迅速清除念珠菌微生物，但当微生物悬浮于加热的正常兔血清中时清除作用增强，而当使用新鲜正常兔血清作为灌注液时清除最为彻底。
