Fuchs E
Prax Klin Pneumol. 1979 Apr;33 Suppl 1:268-76.
"Allergic" manifestations are not necessarily of allergic origin; they can also be produced by non-allergic factors and their true allergic nature must, therefore, be proved. A detailed personal history and the presence of eosinophilia (in the blood or secretions) are suggestive evidence which has to be confirmed by the identification of specific antibodies of the immunoglobulin-E type. Criteria for arriving at the diagnosis "allergy" are (a) demonstration of antibodies by skin and mucous membrane tests with allergen extracts; (b) demonstration of the activity of the identified allergen by challenge tests on the reacting organ (conjunctiva, nose, bronchi); (c) in-vitro demonstration of the allergen-specific immunoglobulin-E by means of the radio-allergo-sorbent test. Details for the performance of the various tests are given and the interpretation and significance of the findings are discussed.
“过敏”表现不一定源于过敏；它们也可能由非过敏因素引起，因此，其真正的过敏性质必须得到证实。详细的个人病史以及嗜酸性粒细胞增多（血液或分泌物中）是提示性证据，必须通过鉴定免疫球蛋白E型特异性抗体来加以证实。做出“过敏”诊断的标准如下：（a）通过使用变应原提取物进行皮肤和黏膜试验来证明抗体的存在；（b）通过对反应器官（结膜、鼻子、支气管）进行激发试验来证明已鉴定变应原的活性；（c）通过放射变应原吸附试验在体外证明变应原特异性免疫球蛋白E的存在。文中给出了各种试验操作的详细信息，并讨论了检测结果的解释及其意义。
