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对精神药物对脑电图影响的监测与评估。

Vigilance and evaluation of psychotropic drug effects on EEG.

作者信息

Bente D

出版信息

Pharmakopsychiatr Neuropsychopharmakol. 1979 Mar;12(2):137-47. doi: 10.1055/s-0028-1094604.

DOI:10.1055/s-0028-1094604
PMID:461501
Abstract

Dynamics and structure of EEG-patterning are highly sensitive indicators of psychotropic drug effects on the regulation of vigilance. Methodological requirements for an adequate evaluation of these effects and appropriate procedures for their measurement are discussed. The kind of information to be obtained by using these strategies is illustrated by the results of comparative investigations concerning the action of Viloxazine, a new antidepressant drug, on the resting activity and on the waking EEG during performance of various tracking tasks.

摘要

脑电图模式的动态变化和结构是精神药物对警觉性调节作用的高度敏感指标。本文讨论了充分评估这些效应的方法学要求及其测量的适当程序。通过关于新型抗抑郁药维洛沙嗪在各种追踪任务执行期间对静息活动和清醒脑电图作用的比较研究结果,说明了使用这些策略可获得的信息类型。

相似文献

1
Vigilance and evaluation of psychotropic drug effects on EEG.对精神药物对脑电图影响的监测与评估。
Pharmakopsychiatr Neuropsychopharmakol. 1979 Mar;12(2):137-47. doi: 10.1055/s-0028-1094604.
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Evaluation of pharmacodynamic properties of psychotropic drugs: quanitative EEG, psychometric and blood level investigations in normals and patients.精神药物的药效学特性评估:正常人和患者的定量脑电图、心理测量及血药浓度研究。
Pharmakopsychiatr Neuropsychopharmakol. 1979 Jan;12(1):45-58. doi: 10.1055/s-0028-1094593.
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[Quantitative EEG in depression (author's transl)].抑郁症中的定量脑电图(作者译)
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[The use of electrophysiological techniques to project typical psychotropic drug effects: some examples (author's transl)].[运用电生理技术预测典型精神药物效应:一些实例(作者译)]
EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1981 Mar;12(1):21-32.
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The influence of psychotropic drugs on the animal EEG: electrophysiological analysis of the effects of psychotropic drugs.精神药物对动物脑电图的影响:精神药物作用的电生理分析。
Electroencephalogr Clin Neurophysiol Suppl. 1982;36:566-76.
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Automatic measurement of the vigilance level and its possible application in psychopharmacology.
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Some examples for the possibilities and limitations of pharmacoelectroencephalography as a method in clinical pharmacology.
Methods Find Exp Clin Pharmacol. 1981;3 Suppl 1:55S-76S.
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Effects of a new psychoactive drug (DU 27716) on different models of rat agonistic behaviour and EEG.一种新型精神活性药物(DU 27716)对大鼠不同攻击行为模型和脑电图的影响。
Prog Clin Biol Res. 1984;169:261-79.
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Classification and evaluation of the pharmacodynamics of psychotropic drugs by single-lead pharmaco-EEG, EEG mapping and tomography (LORETA).通过单导联药物脑电图、脑电图地形图和断层扫描(低分辨率电磁断层成像)对精神药物的药效学进行分类和评估。
Methods Find Exp Clin Pharmacol. 2002;24 Suppl C:97-120.
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Encephalotropic and psychotropic effects of intravenous buflomedil in the elderly: double-blind, placebo-controlled pharmaco-EEG and psychometric studies.老年人静脉注射丁咯地尔的脑趋向性和精神趋向性效应:双盲、安慰剂对照的药物脑电图及心理测量学研究
Int J Clin Pharmacol Res. 1984;4(2):95-107.

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