Badr G, Matousek M
Encephale. 1981;7(4 Suppl):421-7.
Evaluation of the treatment in clinical psychiatry is mostly based on the rating of mental symptoms prior and after treatment. There is an obvious need to supplement clinical observations by objective measurements. Based on EEG automatic analysis, three methods which appeared to be valuable in investigating patients with affective psychosis, are briefly reviewed. 1) The EEG drug profile, indicating changes of the EEG frequency pattern, which varies proportionally to the psychoactive properties of the drug and its metabolites. 2) The fluctuations of the vigilance level which monitor the sedative/excitatory effect of drugs. 3) The interhemispheral assymetry which is related to the intensity of depression.
临床精神病学中对治疗的评估大多基于治疗前后精神症状的评级。显然有必要通过客观测量来补充临床观察。基于脑电图自动分析，简要回顾了三种在研究情感性精神病患者时似乎有价值的方法。1）脑电图药物图谱，表明脑电图频率模式的变化，其与药物及其代谢物的精神活性特性成比例变化。2）警觉水平的波动，用于监测药物的镇静/兴奋作用。3）与抑郁强度相关的半球间不对称性。
