一项关于新型硝基咪唑衍生物Ro 7-0207与甲硝唑治疗有症状肠道阿米巴病的双盲研究。
Double blind study with a new nitroimidazole derivative, Ro 7-0207, versus metronidazole in symptomatic intestinal amebiasis.
作者信息
Botero D
出版信息
Am J Trop Med Hyg. 1974 Sep;23(5):1000-1. doi: 10.4269/ajtmh.1974.23.1000.
PMID:4615595
Abstract
Of 115 patients with symptomatic intestinal amebiasis, 56 were treated with Ro 7-0207 and 59 with metronidazole in a double blind study. Results of treatment were similar in the two groups and side effects were of low intensity except in one patient who received Ro 7-0207 and developed numbness of hands and tongue, difficulty in speaking, and headache. These symptoms disappeared after termination of treatment.
摘要
在一项双盲研究中，115例有症状的肠道阿米巴病患者，56例接受Ro 7-0207治疗，59例接受甲硝唑治疗。两组治疗结果相似，除1例接受Ro 7-0207治疗的患者出现手部和舌部麻木、言语困难和头痛外，副作用强度较低。治疗结束后这些症状消失。
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