半环扁尾海蛇毒素III的一级结构，半环扁尾海蛇毒液中的一种作用较弱且可逆的神经毒素。
The primary structure of the toxin Laticauda semifasciata III, a weak and reversibly acting neurotoxin from the venom of a sea snake, Laticauda semifasciata.
作者信息
Maeda N, Tamiya N
出版信息
Biochem J. 1974 Aug;141(2):389-400. doi: 10.1042/bj1410389.
Abstract
A weak and reversibly acting neurotoxic protein of Laticauda semifasciata venom, Laticauda semifasciata III (component LsIII), was sequenced. Component LsIII consists of 66 amino acid residues and has five disulphide bridges, one of which was located between residues 26 and 30. The weak and reversible neurotoxicity of component LsIII is discussed in relation to its structure, which falls between those of the neuro- and cardiotoxins of sea snakes and Elapidae snakes isolated and sequenced so far.
摘要
对半环扁尾海蛇毒液中一种作用较弱且可逆的神经毒性蛋白——半环扁尾海蛇III（组分LsIII）进行了测序。组分LsIII由66个氨基酸残基组成，有五个二硫键，其中一个位于第26和30位残基之间。结合其结构对组分LsIII较弱且可逆的神经毒性进行了讨论，其结构介于迄今分离并测序的海蛇和眼镜蛇科蛇类的神经毒素和心脏毒素之间。
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本文引用的文献
1
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Biochem J. 1946;40(5-6):628-32. doi: 10.1042/bj0400628.
2
Gel filtration of proteins, peptides and amino acids.蛋白质、肽和氨基酸的凝胶过滤。
Biochim Biophys Acta. 1960 Apr 8;39:193-207. doi: 10.1016/0006-3002(60)90153-0.
3
The preparation and enzymatic hydrolysis of reduced and S-carboxymethylated proteins.还原和S-羧甲基化蛋白质的制备及酶促水解
J Biol Chem. 1963 Feb;238:622-7.
4
Multiple dipping procedures in paper chromatography: a specific test for hydroxy-proline.纸色谱法中的多次浸渍程序：羟脯氨酸的特异性检测
Nature. 1953 Dec 12;172(4389):1100-1. doi: 10.1038/1721100b0.
5
Studies on the metabolism of semen. VIII. Ergothioneine as a normal constituent of boar seminal plasma; purification and crystallization; site of formation and function.精液代谢的研究。VIII. 麦角硫因作为公猪精浆的正常成分；纯化与结晶；形成部位及功能。
Biochem J. 1953 Jan;53(1):140-8. doi: 10.1042/bj0530140.
6
Colour reactions on paper chromatograms by a dipping technique.采用浸渍技术在纸色谱上进行颜色反应。
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7
Studies on the status of free amino and carboxyl groups in cobrotoxin.
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8
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9
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