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慢性活动性肝炎患者血清中的麻疹病毒特异性沉淀素

Measles virus specific precipitins in sera from patients with chronic active hepatitis.

作者信息

Christie K E, Haukenes G

出版信息

Scand J Infect Dis. 1979;11(2):99-106. doi: 10.3109/inf.1979.11.issue-2.01.

Abstract

Measles virus specific antibodies in sera from 29 patients with chronic active hepatitis have been examined using standard serological tests and immunoelectrophoretic techniques. Significantly raised CF antibody titres against measles virus antigen were demonstrated in 50% of the sera. The major immunoprecipitate obtained by immunoelectrophoresis was shown to contain aggregates of measles virus nucleocapsids. Antibodies against the haemagglutinin antigen of the virus envelope were also raised and were demonstrated by line immunoelectrophoresis.

摘要

已采用标准血清学检测和免疫电泳技术检测了29例慢性活动性肝炎患者血清中的麻疹病毒特异性抗体。50%的血清中针对麻疹病毒抗原的补体结合(CF)抗体效价显著升高。免疫电泳获得的主要免疫沉淀物显示含有麻疹病毒核衣壳聚集体。针对病毒包膜血凝素抗原的抗体也有所升高,并通过线状免疫电泳得以证实。

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