血小板中的4-氨基丁酸：2-氧代戊二酸转氨酶
4-aminobutyrate:2-oxoglutarate aminotransferase in blood platelets.
作者信息
White H L
出版信息
Science. 1979 Aug 17;205(4407):696-8. doi: 10.1126/science.462176.
PMID:462176
Abstract
Platelet lysates obtained from blood of humans, dogs, and rats catalyzed the transamination of 4-aminobutyrate with 2-oxoglutarate as cosubstrate. Human platelet 4-aminobutyrate:2-oxoglutarate aminotransferase (36.5 +/- 3.2 picomoles per minute per milligram of platelet protein) resembled the brain enzyme in kinetic properties and in response to cofactors and inhibitors.
摘要
从人、狗和大鼠血液中获得的血小板裂解物，以2-氧代戊二酸作为共底物催化4-氨基丁酸的转氨作用。人血小板4-氨基丁酸：2-氧代戊二酸转氨酶（每毫克血小板蛋白每分钟36.5±3.2皮摩尔）在动力学性质以及对辅因子和抑制剂的反应方面类似于脑酶。
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