攻克癌症的分子基础。
Molecular basis for the attack on cancer.
作者信息
Green M
出版信息
Proc Natl Acad Sci U S A. 1972 Apr;69(4):1036-41. doi: 10.1073/pnas.69.4.1036.
Abstract
Studies of cell transformation by RNA and DNA tumor viruses by DNA-RNA hybridization and extension of these techniques to analysis of human cancer tissue are reviewed. The molecular hybridization technique, it is suggested, will be useful in further studies of the role of oncogenic RNA and/or DNA viruses in causation of cancer.
摘要
本文综述了通过DNA-RNA杂交对RNA和DNA肿瘤病毒引起细胞转化的研究，以及将这些技术扩展用于分析人类癌组织的情况。有人认为，分子杂交技术将有助于进一步研究致癌RNA和/或DNA病毒在癌症病因学中的作用。
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Molecular basis for the attack on cancer.攻克癌症的分子基础。
Proc Natl Acad Sci U S A. 1972 Apr;69(4):1036-41. doi: 10.1073/pnas.69.4.1036.
2
Molecular hybridization: a powerful approach to the detection of viral nucleic acid sequences in human cancer.分子杂交：检测人类癌症中病毒核酸序列的有力方法。
J Natl Cancer Inst. 1972 Jun;48(6):1559-65.
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Cancer virus theories: focus of research debate.癌症病毒理论：研究辩论的焦点
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The RNA tumor viruses--background and foreground.RNA肿瘤病毒——背景与前景
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Oncogenic viruses.致癌病毒。
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Oncogenic adenoviruses.
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Ribodeoxyviruses and cancer.核糖脱氧病毒与癌症
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Oncogenic DNA viruses--replication, tumor gene expression, and role in human cancer.致癌DNA病毒——复制、肿瘤基因表达及其在人类癌症中的作用
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Interference with formation and expression of RNA tumor virus information: rationale and experimental results.对RNA肿瘤病毒信息形成与表达的干扰：原理与实验结果。
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Mechanism of cell transformation by RNA tumor viruses.RNA肿瘤病毒导致细胞转化的机制。
Annu Rev Microbiol. 1971;25:609-48. doi: 10.1146/annurev.mi.25.100171.003141.
引用本文的文献
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Papillomaviruses: a systematic review.乳头瘤病毒：一项系统综述。
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[Molecular basis of viral induced tumors (author's transl)].病毒诱导肿瘤的分子基础（作者译）
Klin Wochenschr. 1973 Aug 15;51(16):781-90. doi: 10.1007/BF01468072.
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Detection of viral DNA sequences in adenovirus-transformed cells by in situ hybridization.通过原位杂交检测腺病毒转化细胞中的病毒DNA序列。
J Virol. 1973 Dec;12(6):1288-92. doi: 10.1128/JVI.12.6.1288-1292.1973.
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Mutation and recombination experiments with yeast as prescreening tests for carcinogenic effects?以酵母进行突变和重组实验作为致癌作用的预筛选试验？
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Characterization of C-type particles produced by a tissue culture-adapted murine myeloma.一种适应组织培养的小鼠骨髓瘤产生的C型颗粒的特性分析。
J Virol. 1973 Dec;12(6):1589-97. doi: 10.1128/JVI.12.6.1589-1597.1973.
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In situ hybridization of RD114-virus RNA with human metaphase chromosomes.RD114病毒RNA与人中期染色体的原位杂交。
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Do highly oncogenic group A human adenoviruses cause human cancer? Analysis of human tumors for adenovirus 12 transforming DNA sequences.高致癌性的A组人类腺病毒会引发人类癌症吗？对人类肿瘤进行腺病毒12转化DNA序列分析。
Proc Natl Acad Sci U S A. 1976 Dec;73(12):4657-61. doi: 10.1073/pnas.73.12.4657.
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Intracellular forms of adenovirus DNA. V. Viral DNA sequences in hamster cells abortively infected and transformed with human adenovirus type 12.腺病毒DNA的细胞内形式。V. 用12型人腺病毒进行流产感染和转化的仓鼠细胞中的病毒DNA序列
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Transcription of the genome of adenovirus type 12. III. Maps of stable RNA from productively infected human cells and abortively infected and transformed hamster cells.腺病毒12型基因组的转录。III. 来自有效感染的人类细胞以及流产感染和转化的仓鼠细胞的稳定RNA图谱。
J Virol. 1976 Nov;20(2):355-72. doi: 10.1128/JVI.20.2.355-372.1976.
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