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一种适应组织培养的小鼠骨髓瘤产生的C型颗粒的特性分析。

Characterization of C-type particles produced by a tissue culture-adapted murine myeloma.

作者信息

Volkman L E, Krueger R G

出版信息

J Virol. 1973 Dec;12(6):1589-97. doi: 10.1128/JVI.12.6.1589-1597.1973.

DOI:10.1128/JVI.12.6.1589-1597.1973
PMID:4128386
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC356802/
Abstract

C-type particles produced by a tissue culture-adapted BALB/c myeloma were characterized. It was determined that although the particles were morphologically and antigenically similar to murine leukemia and sarcoma virus, the size of their RNA was different, they lacked RNA-dependent DNA polymerase, they were unstable in NET buffer, sucrose and citrate but were stable in glycerol and Earle balanced salt solution, and they behaved differently from oncornaviruses when treated with ether and detergent.

摘要

对一种经组织培养适应的BALB/c骨髓瘤产生的C型颗粒进行了特性鉴定。已确定，尽管这些颗粒在形态和抗原性上与鼠白血病和肉瘤病毒相似，但其RNA大小不同，缺乏RNA依赖性DNA聚合酶，在NET缓冲液、蔗糖和柠檬酸盐中不稳定，但在甘油和Earle平衡盐溶液中稳定，并且在用乙醚和去污剂处理时其行为与肿瘤病毒不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7683/356802/5c0e67e3fdc3/jvirol00264-0414-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7683/356802/5c0e67e3fdc3/jvirol00264-0414-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7683/356802/5c0e67e3fdc3/jvirol00264-0414-a.jpg

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本文引用的文献

1
INDUCTION OF PLASMA CELL TUMORS AND SARCOMAS IN MICE BY DIFFUSION CHAMBERS PLACED IN THE PERITONEAL CAVITY.通过置于腹腔的扩散小室在小鼠中诱导浆细胞瘤和肉瘤
J Natl Cancer Inst. 1963 Oct;31:997-1017.
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The detection and study of tumor viruses with the electron microscope.利用电子显微镜对肿瘤病毒进行检测与研究。
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Electron microscopy of tumor cells and tumor viruses; a review.肿瘤细胞与肿瘤病毒的电子显微镜检查；综述
鸡卵黄可稳定培养的MOPC - 315小鼠骨髓瘤细胞产生的C型颗粒中的逆转录酶活性。
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Intracisternal A particles from FLOPC-1 BALB/c myeloma: presence of high-molecular-weight RNA and RNA-dependent DNA polymerase.来自FLOPC-1 BALB/c骨髓瘤的脑池内A颗粒：高分子量RNA和RNA依赖性DNA聚合酶的存在。
J Virol. 1976 May;18(2):745-56. doi: 10.1128/JVI.18.2.745-756.1976.
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Relationships between intracisternal type A and extracellular oncornavirus-like particles produced in murine MOPC-460 myeloma cells.小鼠MOPC-460骨髓瘤细胞中产生的A型脑池内病毒与细胞外肿瘤病毒样颗粒之间的关系。
J Virol. 1976 Apr;18(1):344-55. doi: 10.1128/JVI.18.1.344-355.1976.
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Host range studies of FLOPC-1 murine myeloma C particles.FLOPC-1小鼠骨髓瘤C颗粒的宿主范围研究。
J Virol. 1975 Nov;16(5):1137-45. doi: 10.1128/JVI.16.5.1137-1145.1975.
7
Characterization of DNA polymerase and RNA associated with A-type particles from murine myeloma cells.与小鼠骨髓瘤细胞A型颗粒相关的DNA聚合酶和RNA的特性分析
J Virol. 1975 Feb;15(2):407-15. doi: 10.1128/JVI.15.2.407-415.1975.
Cancer Res. 1958 Jun;18(5):491-509.
4
Leukemogenic activity of ether-extracted Rauscher leukemia virus.经乙醚提取的劳斯氏白血病病毒的致白血病活性
Science. 1967 Jun 23;156(3782):1610-3. doi: 10.1126/science.156.3782.1610.
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