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[剥夺后视觉功能恢复期间兔脑外侧膝状体神经元的细胞化学特征]

[Cytochemical characteristics of the neurons of the external geniculate body in the rabbit brain in a period of visual function recovery after deprivation].

作者信息

Golikova T L

出版信息

Tsitologiia. 1979 May;21(5):525-30.

PMID:462537
Abstract

To study the properties of the external geniculate body, both neuron protein concentration and content were measured cytophotometrically in the cytoplasm of the above neurons taken from nomal animals and animals transported to normal conditions of illumination only after 2.5 months of visual deprivation, where they were put just after birth. The normalization of protein concentration and content has been observed in the neuron cytoplasm and in the surrounding structures. The magnitude of changes observed was related to the size of the neurons. It is supposed that some portion of neurons may exist in the external geniculate body having different degrees of dependence upon the visual impulsation. Mechanisms of possible rearrangement of the neuron metabolism in the geniculate body during the restoring period are discussed.

摘要

为研究外侧膝状体的特性,采用细胞光度法测定了取自正常动物以及出生后即处于视觉剥夺状态、仅在2.5个月后才转入正常光照条件下的动物的上述神经元胞质中的神经元蛋白质浓度和含量。已观察到神经元胞质及其周围结构中蛋白质浓度和含量的正常化。所观察到的变化程度与神经元大小有关。推测外侧膝状体中可能存在一部分对视觉冲动有不同程度依赖性的神经元。文中讨论了恢复期间膝状体中神经元代谢可能重新排列的机制。

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