Crichton E P, McDonnell C E
Can Med Assoc J. 1972 Aug 19;107(4):292-5.
In a series of 52 patients the combination of trimethoprim and sulfamethoxazole was used for the treatment of urinary tract infection and the results are analyzed with respect to the clinical diagnosis and bacterial etiology. There was complete agreement between in vitro sensitivity and clinical response except in the case of one strain of Streptococcus fecalis. The combination of drugs was effective against some bacterial strains which were resistant to the commonly used antimicrobial agents.
在一组52例患者中,使用甲氧苄啶和磺胺甲恶唑联合治疗尿路感染,并根据临床诊断和细菌病因对结果进行分析。除了一株粪链球菌外,体外药敏试验结果与临床反应完全一致。该联合用药对一些对常用抗菌药物耐药的菌株有效。