Edmonds P, Suskind R R, Macmillan B G, Holder I A
Appl Microbiol. 1972 Aug;24(2):213-8. doi: 10.1128/am.24.2.213-218.1972.
In a retrospective study 36 cultures of Pseudomonas aeruginosa, isolated from patients with fatal Pseudomonas burn wound sepsis and from burned patients with nonfatal P. aeruginosa infections, were used to evaluate the consistency and reliability of serological, phage, and pyocin typing as epidemiological tools. Frequency distributions of positive reactions were analyzed by a computer in a 3-way chi-square test, and a high degree of consistency was demonstrated for each method. From these data, 75% of the cultures were differentiated by serological, 90% by phage, and 100% by pyocin typing. There was no significant difference among organisms isolated from fatal cases of burn wound sepsis and organisms from patients with nonfatal infections (chi(2) = 0.3418; P = 0.9870). The combined typing system was a sensitive and reliable epidemiological tool for intraspecific differentiation of P. aeruginosa.
在一项回顾性研究中，从患有致命性铜绿假单胞菌烧伤创面败血症的患者以及患有非致命性铜绿假单胞菌感染的烧伤患者中分离出36株铜绿假单胞菌培养物，用于评估血清学、噬菌体和细菌素分型作为流行病学工具的一致性和可靠性。通过计算机在三向卡方检验中分析阳性反应的频率分布，结果表明每种方法都具有高度的一致性。根据这些数据，75%的培养物可通过血清学分型区分，90%可通过噬菌体分型区分，100%可通过细菌素分型区分。从烧伤创面败血症致命病例中分离出的菌株与非致命感染患者的菌株之间没有显著差异（卡方值=0.3418；P=0.9870）。联合分型系统是用于铜绿假单胞菌种内区分的敏感且可靠的流行病学工具。
