用于检测抗脑膜炎球菌多糖抗体的乳胶凝集试验。
Latex agglutination test for measurement of antibodies to meningococcal polysaccharides.
作者信息
Tramont E C, Artenstein M S
出版信息
Infect Immun. 1972 Mar;5(3):346-51. doi: 10.1128/iai.5.3.346-351.1972.
Abstract
A latex agglutination test employing serogroup-specific meningococcal polysaccharides as the antigen has been developed. The test has been used to measure serological responses in patients with meningococcal disease, in meningococcal carriers, and in volunteers who received meningococcal vaccines. It has been shown to be a sensitive and highly specific test for the detection of group-specific meningococcal antibody. The advantages of standardized particles and antigens which are simple to prepare and stable make this assay feasible for many nonspecialized or small laboratories.
摘要
一种采用血清群特异性脑膜炎球菌多糖作为抗原的乳胶凝集试验已被开发出来。该试验已用于检测患脑膜炎球菌病的患者、脑膜炎球菌携带者以及接种脑膜炎球菌疫苗的志愿者的血清学反应。它已被证明是一种检测群特异性脑膜炎球菌抗体的灵敏且高度特异的试验。标准化颗粒和抗原制备简单且稳定，这些优点使得该检测方法对许多非专业或小型实验室来说切实可行。
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