• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑膜炎奈瑟菌X群多糖抗原的物理化学性质

Physicochemical properties of Neisseria meningitidis group X polysaccharide antigen.

作者信息

Apicella M A, Robinson J A

出版信息

Infect Immun. 1972 Nov;6(5):773-8. doi: 10.1128/iai.6.5.773-778.1972.

DOI:10.1128/iai.6.5.773-778.1972
PMID:4629206
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC422609/
Abstract

Neisseria meningitidis group X occurs in human carrier populations and is rarely implicated in serious disease. This organism possesses a capsular group antigen which is an acidic polysaccharide. It is composed of the amino sugars, glucosamine, glucosamine-6-phosphate, galactosamine, and the simple hexose, glucose. The group X capsular antigen has an S(20,w) (0) of 3.6, and the acidic nature of the polysaccharide is reflected in an isoelectric point of 3.65. The meningococcal A, B, C, and Y polysaccharide group antigens are also composed primarily of amino sugars. The chemical composition of the group X antigen most closely resembles the capsular antigen of N. meningitidis group Y, which is also predominately a carrier organism.

摘要

X群脑膜炎奈瑟菌存在于人类带菌人群中,很少引发严重疾病。这种微生物拥有一种荚膜群抗原,该抗原是一种酸性多糖。它由氨基糖、葡萄糖胺、6-磷酸葡萄糖胺、半乳糖胺和简单的己糖葡萄糖组成。X群荚膜抗原的沉降系数S(20,w) (0)为3.6,多糖的酸性性质反映在其3.65的等电点上。脑膜炎球菌A、B、C和Y群多糖抗原也主要由氨基糖组成。X群抗原的化学组成与Y群脑膜炎奈瑟菌的荚膜抗原最为相似,Y群脑膜炎奈瑟菌也主要是一种带菌微生物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6bf/422609/de27a870cec3/iai00275-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6bf/422609/de27a870cec3/iai00275-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6bf/422609/de27a870cec3/iai00275-0126-a.jpg

相似文献

1
Physicochemical properties of Neisseria meningitidis group X polysaccharide antigen.脑膜炎奈瑟菌X群多糖抗原的物理化学性质
Infect Immun. 1972 Nov;6(5):773-8. doi: 10.1128/iai.6.5.773-778.1972.
2
Identification of a subgroup antigen on the Neisseria meningitidis group C capsular polysaccharide.脑膜炎奈瑟菌C群荚膜多糖上一种亚组抗原的鉴定。
J Infect Dis. 1974 Feb;129(2):147-53. doi: 10.1093/infdis/129.2.147.
3
Immunochemical similarity between polysaccharide antigens of Escherichia coli 07: K1(L):NM and group B Neisseria meningitidis.大肠杆菌O7:K1(L):NM的多糖抗原与B群脑膜炎奈瑟菌之间的免疫化学相似性。
J Immunol. 1973 Jan;110(1):262-8.
4
Elaboration of both the group W135 and group Y capsular polysccharides by a single strain of Neisseria meningitidis.一株脑膜炎奈瑟菌对W135群和Y群荚膜多糖的合成。
J Gen Microbiol. 1980 May;118(1):39-43. doi: 10.1099/00221287-118-1-39.
5
A radioactive antigen-binding assay for Neisseria meningitidis polysaccharide antibody.一种用于检测脑膜炎奈瑟菌多糖抗体的放射性抗原结合试验。
J Immunol. 1972 Apr;108(4):913-20.
6
Isolation and characterization of a native cell wall complex from Neisseria meningitidis.脑膜炎奈瑟菌天然细胞壁复合物的分离与鉴定
Infect Immun. 1972 Nov;6(5):835-51. doi: 10.1128/iai.6.5.835-851.1972.
7
Classification of Neisseria meningitidis group B into distinct serotypes. IV. Preliminary chemical studies on the nature of the serotype antigen.B群脑膜炎奈瑟菌不同血清型的分类。IV. 血清型抗原性质的初步化学研究。
Infect Immun. 1972 Nov;6(5):674-81. doi: 10.1128/iai.6.5.674-681.1972.
8
Classification of Neisseria meningitidis group B into distinct serotypes. 3. Application of a new bactericidal-inhibition technique to distribution of serotypes among cases and carriers.B群脑膜炎奈瑟菌的不同血清型分类。3. 一种新的杀菌抑制技术在病例和携带者血清型分布中的应用。
J Infect Dis. 1973 Feb;127(2):149-54. doi: 10.1093/infdis/127.2.149.
9
[Insoluble antigens in the identification of Cl. botulinum. 3. Chemical studies of polysaccharides].
Pol Arch Weter. 1973;16(1):65-83.
10
Immunological investigations of meningococcal disease. II. Some characteristics of group C antigen of Neisseria meningitidis in the sera of patients with fulminant meningococcemia.脑膜炎球菌病的免疫学研究。II.暴发性脑膜炎球菌血症患者血清中脑膜炎奈瑟菌C群抗原的一些特征。
J Infect Dis. 1974 May;129(5):538-44. doi: 10.1093/infdis/129.5.538.

引用本文的文献

1
The meningococcus and mechanisms of pathogenicity.脑膜炎球菌与致病机制
Microbiol Rev. 1982 Jun;46(2):162-90. doi: 10.1128/mr.46.2.162-190.1982.
2
Immunological and biochemical studies of meningococcal C polysaccharides isolated by diethylaminoethyl chromatography.通过二乙氨基乙基色谱法分离的脑膜炎球菌C多糖的免疫学和生化研究。
Infect Immun. 1976 Jul;14(1):106-13. doi: 10.1128/iai.14.1.106-113.1976.

本文引用的文献

1
Physicochemical Properties of Neisseria meningitidis Group C and Y Polysaccharide Antigens.脑膜炎奈瑟菌 C 群和 Y 群多糖抗原的理化性质。
Infect Immun. 1970 Oct;2(4):392-7. doi: 10.1128/iai.2.4.392-397.1970.
2
Isolation and Characterization of Neisseria meningitidis Groups A, C, X, and Y Polysaccharide Antigens.A、C、X 和 Y 群脑膜炎奈瑟菌多糖抗原的分离与特性。
Infect Immun. 1970 Jan;1(1):8-14. doi: 10.1128/iai.1.1.8-14.1970.
3
Meningococcus carrier rates and meningitis incidence.脑膜炎球菌带菌率和脑膜炎发病率。
Bacteriol Rev. 1950 Jun;14(2):115-60. doi: 10.1128/br.14.2.115-160.1950.
4
Spectrophotometric method for the determination of free pentose and pentose in nucleotides.用于测定核苷酸中游离戊糖和戊糖的分光光度法。
J Biol Chem. 1949 Nov;181(1):379-92.
5
Diffusion-in-gel methods for immunological analysis. II.凝胶扩散免疫分析方法。II.
Prog Allergy. 1962;6:30-154. doi: 10.1159/000313795.
6
The biosynthesis of sialic acids.唾液酸的生物合成。
J Biol Chem. 1962 May;237:1421-31.
7
Biosynthesis of sialic acids by Neisseria meningitidis.脑膜炎奈瑟菌对唾液酸的生物合成
J Biol Chem. 1962 Nov;237:3520-6.
8
A modified uronic acid carbazole reaction.一种改良的糖醛酸咔唑反应。
Anal Biochem. 1962 Oct;4:330-4. doi: 10.1016/0003-2697(62)90095-7.
9
The thiobarbituric acid assay of sialic acids.唾液酸的硫代巴比妥酸测定法。
J Biol Chem. 1959 Aug;234(8):1971-5.
10
The lethal effect of endotoxins on the chick embryo.内毒素对鸡胚的致死作用。
J Exp Med. 1956 Aug 1;104(2):217-31. doi: 10.1084/jem.104.2.217.