Schreiber A, Oliveira L G, Cserhati M, Jacob H A
Z Orthop Ihre Grenzgeb. 1979 Apr;117(2):151-5.
Histological examinations (including tetracycline labelling) of preparations of the neck of the femur which had to be removed 1 1/2, 3 and 14 1/2 months subsequent to double-cup arthroplasty according to Freeman, prove that the bone tissue can remain vital under the solidly cemented metal cup. A thick layer of connective tissue with bundles of collagenous fibres running parallel to the surface, is temporarily formed between the cement layer and the prepared spongiosa of the neck of the femur. It is possible that this layer of connective tissue is replaced within about a years' time by a thin, lamellar cortex layer, which is then covered only by a thin layer of connective tissue which is rich in fibres. Below this layer, the spongiosa spaces are definitely widened and filled with fibrotic fat marrow; vascularisation decreases, whereas osteoporosis increases.
根据弗里曼的方法,对双杯关节成形术后1个半月、3个月和14个半月必须切除的股骨颈标本进行组织学检查(包括四环素标记),结果证明,在牢固固定的金属杯下,骨组织可以保持活力。在骨水泥层与股骨颈准备好的松质骨之间,暂时形成一层厚的结缔组织,其中有平行于表面的胶原纤维束。这层结缔组织有可能在大约一年的时间内被一层薄的板层皮质层所取代,然后仅被一层富含纤维的薄结缔组织所覆盖。在这层之下,松质骨间隙明显增宽,充满纤维化的脂肪骨髓;血管化减少,而骨质疏松增加。