A personal series of 16 patients treated with Nissen fundoplication for reflux peptic esophagitis with or without hiatal hernia between March 1975 and September 1977 is presented. The average length of followup was 18 months. The age range was 21 to 78. Very good to excellent results were achieved in 94% with a 12.5% morbidity, 6% operative complication rate and 0 mortality. This relatively simple procedure definitely reduces, if not cures, the symptomatology of the often "miserable" patient with intractable reflux peptic esophagitis. The encouraging reports in the recent literature concerning patients treated with this operation recommend its wider use in the future.
本文介绍了1975年3月至1977年9月期间,采用Nissen胃底折叠术治疗16例伴有或不伴有食管裂孔疝的反流性消化性食管炎患者的个人病例系列。平均随访时间为18个月。年龄范围为21至78岁。94%的患者取得了非常好至极好的效果,发病率为12.5%,手术并发症发生率为6%,死亡率为0。这种相对简单的手术即使不能治愈,也肯定能减轻那些患有顽固性反流性消化性食管炎的“痛苦”患者的症状。近期文献中关于接受该手术患者的令人鼓舞的报告建议在未来更广泛地应用此手术。