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Secretion of dopa in phaeochromocytoma.

作者信息

Louis W J, Doyle A E, Heath W C, Robinson M J

出版信息

Br Med J. 1972 Nov 11;4(5836):325-7. doi: 10.1136/bmj.4.5836.325.

Abstract

In a series of 11 cases with phaeochromocytoma, two patients were found in whom the tumour secreted dopa in addition to dopamine, noradrenaline, and adrenaline. These two patients were normotensive in spite of high plasma and urinary levels of noradrenaline and adrenaline. This raises the possibility that dopa may be able to protect against the hypertensive action of noradrenaline. Such a mechanism would also explain the absence of hypertension in many cases of neuroblastoma.

摘要

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本文引用的文献

3
Direct cardiac effects of dopamine.多巴胺对心脏的直接作用。
Circ Res. 1962 Jan;10:68-72. doi: 10.1161/01.res.10.1.68.
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Catecholamine metabolism in patients with pheochromocytoma.
Pharmacol Rev. 1959 Jun;11(2, Part 2):374-8.
5
The depressor action of dopamine and adrenaline.多巴胺和肾上腺素的降压作用。
Br J Pharmacol Chemother. 1958 Dec;13(4):471-9. doi: 10.1111/j.1476-5381.1958.tb00240.x.
8
Hydroxytyramine and the adrenal medulla.羟酪胺与肾上腺髓质。
J Physiol. 1953 Apr 28;120(1-2):15-9. doi: 10.1113/jphysiol.1953.sp004868.
10
Catecholamines.
N Engl J Med. 1965 Sep 30;273(14):746-53 concl. doi: 10.1056/NEJM196509302731406.

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