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血液透析中的急性锌中毒

Acute zinc toxicity in haemodialysis.

作者信息

Gallery E D, Blomfield J, Dixon S R

出版信息

Br Med J. 1972 Nov 11;4(5836):331-3. doi: 10.1136/bmj.4.5836.331.

Abstract

A country patient on home haemodialysis suffered acute nausea, vomiting, and fever during dialyses when she used water stored in a galvanized tank. She subsequently was found to have severe anaemia with raised plasma and erythrocyte zinc concentrations. Intercurrent hospital haemodialyses and subsequent home dialyses with deionized water were symptom-free.Experimental haemodialyses of dogs against small concentrations of zinc showed a disproportionate rise in plasma zinc and possible uptake of zinc by the liver.

摘要

一名接受家庭血液透析的乡村患者在使用储存在镀锌水箱中的水进行透析时,出现了急性恶心、呕吐和发热症状。随后发现她患有严重贫血,血浆和红细胞锌浓度升高。在医院进行的间歇性血液透析以及随后使用去离子水进行的家庭透析均未出现症状。对狗进行的针对低浓度锌的实验性血液透析显示,血浆锌出现不成比例的升高,并且肝脏可能摄取了锌。

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