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兔腹膜巨噬细胞的杀葡萄球菌能力与感染及激发的关系:迟发型超敏反应但抵抗力未增强。

Staphylococcidal capability of rabbit peritoneal macrophages in relation to infection and elicitation: delayed-type hypersensitivity without increased resistance.

作者信息

Lenhart N, Mudd S

出版信息

Infect Immun. 1972 May;5(5):757-62. doi: 10.1128/iai.5.5.757-762.1972.

Abstract

The staphylococcidal capability of populations of peritoneal macrophages in rabbits has been measured before and after repeated infections with Staphylococcus aureus. Such rabbits after infection showed delayed-type hypersensitivity to S. aureus antigens, but the staphylococcidal capability of the peritoneal macrophages was not increased. This result at the cellular level is in agreement with previous assessment in vivo of the consequences of staphylococcal infection. Pathways to cell-mediated resistance, with and without delayed-type hypersensitivity, are presented.

摘要

在兔群中,对金黄色葡萄球菌进行反复感染前后,均已测定了腹膜巨噬细胞群体的杀葡萄球菌能力。感染后的此类兔子对金黄色葡萄球菌抗原表现出迟发型超敏反应,但腹膜巨噬细胞的杀葡萄球菌能力并未增强。这一细胞水平的结果与先前对葡萄球菌感染后果的体内评估一致。本文还介绍了有和没有迟发型超敏反应的细胞介导抗性途径。

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本文引用的文献

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