Targowski S P, Berman D T
Infect Immun. 1974 Jan;9(1):41-3. doi: 10.1128/iai.9.1.41-43.1974.
Protracted inflammatory dermal reactions to staphylococcal cell walls were observed in guinea pigs passively sensitized by transfer of peritoneal exudate cells but not by immune serum from guinea pigs actively sensitized with heat-killed cells of Staphylococcus aureus. The experiments verify the hypothesis that the protracted reaction is a cell-mediated immune response which is resolvable from the toxicity of the cell walls.
在通过转移腹腔渗出细胞而被动致敏的豚鼠中,观察到对葡萄球菌细胞壁的持续性炎症性皮肤反应,但在用金黄色葡萄球菌热灭活细胞主动致敏的豚鼠的免疫血清致敏的情况下未观察到这种反应。这些实验证实了以下假设:持续性反应是一种细胞介导的免疫反应,可与细胞壁的毒性区分开来。