Atkinson W J
Lancet. 1975 Jan 4;1(7897):5-9. doi: 10.1016/s0140-6736(75)92371-5.
In six cases an attempt was made to relieve the tension on intracranial aneurysms by temporarily clamping the internal carotid artery in the neck, so as to increase the expansibility of the artery. This approach was based on the concept (or "A principle") that haemorrhage is caused by the aneurysm having to bear the full force of systolic pulse pressure when atherosclerosis prevents this pressure being taken up by the normally expansile arterial wall. Follow-up has been fairly short, but the preliminary findings in four of the six patients are encouraging. More attention must be paid in the future to the significance of atherosclerosis in the onset of bleeding from intracranial aneurysms and the incidence of postoperative problems. The argument that atherosclerosis permits the transmission of the systolic pulse directly to the aneurysm wall requires further investigation. The earlier pathological signs of atherosclerosis must receive greater attention, and post-mortem study of the walls of arteries in immediate juxtaposition to aneurysms with high-powered magnification is required.
在6例患者中,尝试通过临时夹闭颈部的颈内动脉来缓解颅内动脉瘤的张力,以增加动脉的可扩张性。这种方法基于这样一种概念(或“一个原则”),即当动脉粥样硬化阻止正常可扩张的动脉壁吸收收缩期脉压时,动脉瘤必须承受收缩期脉压的全部力量,从而导致出血。随访时间相当短,但6例患者中有4例的初步结果令人鼓舞。未来必须更加关注动脉粥样硬化在颅内动脉瘤出血发作中的意义以及术后问题的发生率。动脉粥样硬化使收缩期脉搏直接传递到动脉瘤壁的观点需要进一步研究。动脉粥样硬化的早期病理迹象必须得到更多关注,并且需要用高倍放大镜对紧邻动脉瘤的动脉壁进行尸检研究。