Heerema M S, Ein M E, Musher D M, Bradshaw M W, Williams T W
Am J Med. 1979 Aug;67(2):219-27. doi: 10.1016/0002-9343(79)90394-2.
Anaerobic meningitis occurred in four patients in whom anaerobic bacteria had not been suspected as a possible cause. The predisposing conditions were typical of those seen in patients previously reported to have this infection and included chronic otitis media with mastoiditis, chronic sinusitis, recent craniotomy and abdominal trauma. Two of the patients had undergone immunosuppression (immunosuppressed patients); a compromised immune system may facilitate the development of anaerobic meningitis in patients with the appropritate underlying conditions. Head and neck neoplasms, head trauma, suppurative pharyngitis and laminectomy wounds are additional situations in which anaerobic meningitis occurs. Anaerobic bacterial meningitis probably occurs more often than is recognized. The cerebrospinal fluid should be transported and cultured anaerobically when meningitis develops in a patient with a predisposing condition.
4例患者发生了厌氧性脑膜炎，此前并未怀疑厌氧菌可能是病因。诱发因素与先前报道的患有这种感染的患者所见典型因素相同，包括伴有乳突炎的慢性中耳炎、慢性鼻窦炎、近期开颅手术和腹部创伤。其中2例患者接受过免疫抑制治疗（免疫抑制患者）；免疫系统受损可能会促使有适当基础疾病的患者发生厌氧性脑膜炎。头颈部肿瘤、头部外伤、化脓性咽炎和椎板切除术后伤口是发生厌氧性脑膜炎的其他情况。厌氧性细菌性脑膜炎的发生可能比已认识到的更为常见。当有诱发因素的患者发生脑膜炎时，脑脊液应进行厌氧运输和培养。
