Siegler D, Faiers M C, Willis A T
Postgrad Med J. 1982 Sep;58(683):560-1. doi: 10.1136/pgmj.58.683.560.
A 70-year-old man with a history of chronic middle and external ear suppuration presenting with acute meningitis due to is described. Anaerobic organisms including species were cultured from the affected external auditory meatus. Administration of metronidazole led to complete clinical recovery and a cholesteatoma was subsequently surgically evacuated. Chronic suppuration in the middle ear and paranasal sinuses is the commonest primary cause of cerebral abscess and in this setting meningitis is associated with a particularly high mortality. The major role of anaerobic sepsis in otolaryngological practice is well established. Metronidazole is the chemotherapeutic agent of choice.
本文描述了一名70岁男性,有慢性中耳和外耳道化脓病史,因[具体病因未给出]导致急性脑膜炎。从受影响的外耳道培养出包括[具体菌种未给出]在内的厌氧菌。甲硝唑治疗使患者临床完全康复,随后手术清除了胆脂瘤。中耳和鼻窦的慢性化脓是脑脓肿最常见的主要原因,在这种情况下,脑膜炎的死亡率特别高。厌氧菌败血症在耳鼻喉科实践中的主要作用已得到充分证实。甲硝唑是首选的化疗药物。