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Aldehydes as inhibitors of papain.

作者信息

Westerik J O, Wolfenden R

出版信息

J Biol Chem. 1972 Dec 25;247(24):8195-7.

PMID:4640942
Abstract
摘要

相似文献

1
Aldehydes as inhibitors of papain.醛类作为木瓜蛋白酶的抑制剂。
J Biol Chem. 1972 Dec 25;247(24):8195-7.
2
The use of crystallography, graphics, and quantitative structure--activity relationships in the analysis of the papain hydrolysis of X-phenyl hippurates.
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13C NMR study of the stereospecificity of the thiohemiacetals formed on inhibition of papain by specific enantiomeric aldehydes.特定对映体醛抑制木瓜蛋白酶时形成的硫代半缩醛立体特异性的 13C 核磁共振研究。
Biochemistry. 1986 Apr 22;25(8):2293-8. doi: 10.1021/bi00356a066.
4
Nonpolar effects in reactions of the sulfhydryl group of papain.木瓜蛋白酶巯基反应中的非极性效应。
Biochemistry. 1970 Aug 18;9(17):3348-52. doi: 10.1021/bi00819a009.
5
Effects of pH, concentration and aging on the malonaldehyde reaction with proteins.
Lipids. 1972 Apr;7(4):229-33. doi: 10.1007/BF02533218.
6
Inhibition of papain by N-ethylmaleimide.
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7
Se-Aryl selenenylthiosulphates and S-aryl sulphenylthiosulphates as thiol-blocking reagents.作为硫醇阻断剂的硒芳基硫代亚硫酸盐和硫芳基亚磺酰基硫代硫酸盐。
Biochem J. 1984 Aug 1;221(3):797-801. doi: 10.1042/bj2210797.
8
On the mechanism of action of streptococcal proteinase. II. Comparison of the kinetics of proteinase- and papain-catalyzed hydrolysis of N-acylamino acid esters.论链球菌蛋白酶的作用机制。II. 蛋白酶和木瓜蛋白酶催化N-酰基氨基酸酯水解动力学的比较
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Thiohemiacetal formation by inhibitory aldehydes at the active site of papain.
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10
Proflavine interactions with papain and ficin. II. Effects of dye binding upon reversible inhibition.
Biochemistry. 1974 May 7;13(10):2087-92. doi: 10.1021/bi00707a014.

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Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin.糜蛋白酶抑制剂复合物中的半缩醛稳定作用以及糜蛋白酶催化丝氨酸残基羟基的反应活性。
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