体外肺结缔组织细胞的激活
Activation of lung connective tissue cells in vitro.
作者信息
Castor C W, Wilson S M, Heiss P R, Seidman J C
出版信息
Am Rev Respir Dis. 1979 Jul;120(1):101-6. doi: 10.1164/arrd.1979.120.1.101.
PMID:464373
Abstract
Guinea pig lung fibroblasts "activated" in vitro by exposure to connective tissue-activating peptides I and III, and guinea pig tissue extracts showed enhanced glycolysis and accelerated glycosaminoglycan synthesis. Formation of hyaluronic acid, and to a lesser extent, chondroitin 4/6-sulfate was stimulated by these agents.
摘要
通过暴露于结缔组织激活肽I和III在体外“激活”的豚鼠肺成纤维细胞，以及豚鼠组织提取物显示出糖酵解增强和糖胺聚糖合成加速。这些物质刺激了透明质酸的形成，以及程度较轻的硫酸软骨素4/6的形成。
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