Smith M, Payne R B
Ann Clin Biochem. 1979 Mar;16(2):96-9. doi: 10.1177/000456327901600119.
The drug paracetamol (N-acetyl-p-aminophenol; acetaminophen) caused a spurious increase in serum uric acid measured by phosphotungstic acid reduction methods. However, the increase was less than 0.12 mmol/1 at plasma levels of paracetamol found in overdosage (40 mg/100 ml) and was small at therapeutic concentrations (less than 4 mg/100 ml). It is concluded that few patients with joint pain who have taken paracetamol paracetamol as an analgesic will have clinically misleading values for serum uric acid.
药物对乙酰氨基酚（N - 乙酰 - 对氨基酚；醋氨酚）通过磷钨酸还原法测定会导致血清尿酸假性升高。然而，在过量服用（40毫克/100毫升）时所达到的对乙酰氨基酚血浆水平下，尿酸升高幅度小于0.12毫摩尔/升，在治疗浓度（小于4毫克/100毫升）时升高幅度较小。结论是，服用对乙酰氨基酚作为镇痛药的关节疼痛患者中，很少会出现血清尿酸值在临床上产生误导的情况。
