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J Clin Pathol. 1972 Oct;25(10):867-71. doi: 10.1136/jcp.25.10.867.
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本文引用的文献

1
THE RELATIONSHIP BETWEEN INTELLIGENCE AND BIRTH WEIGHT IN TWINS.双胞胎的智力与出生体重之间的关系。
Neurology. 1965 Apr;15:341-7. doi: 10.1212/wnl.15.4.341.
2
MALNUTRITION: PROBABLE CAUSE OF FETAL GROWTH RETARDATION.营养不良:胎儿生长受限的可能原因。
Arch Pathol. 1965 Mar;79:284-91.
3
EXPERIMENTAL GROWTH RETARDATION IN THE FOETAL RAT.实验性胎儿大鼠生长迟缓
J Pathol Bacteriol. 1964 Jul;88:1-13.
4
GROWTH AND DEVELOPMENT OF TWINS OF DISSIMILAR SIZE AT BIRTH.出生时大小不同的双胞胎的生长与发育
Pediatrics. 1964 Mar;33:327-33.
5
CHRONIC FETAL DISTRESS AND PLACENTAL INSUFFICIENCY.慢性胎儿窘迫与胎盘功能不全。
Biol Neonat. 1963;5:215-65. doi: 10.1159/000239870.
6
INTRAUTERINE GROWTH AS ESTIMATED FROM LIVEBORN BIRTH-WEIGHT DATA AT 24 TO 42 WEEKS OF GESTATION.根据孕24至42周活产儿出生体重数据估算的宫内生长情况。
Pediatrics. 1963 Nov;32:793-800.
7
Low content of cerebral lipids in infants suffering from malnutrition.营养不良婴儿大脑脂质含量低。
Nature. 1969 Feb 8;221(5180):552-3. doi: 10.1038/221552a0.
8
Head circumference and cellular growth of the brain in normal and marasmic children.正常儿童和消瘦型营养不良儿童的头围及脑的细胞生长情况
J Pediatr. 1969 May;74(5):774-8. doi: 10.1016/s0022-3476(69)80140-x.
9
The determination of normal ranges from routine laboratory data.根据常规实验室数据确定正常范围。
Clin Chem. 1968 Oct;14(10):979-88.
10
Changes in brain weight, cholesterol, phospholipid, and DNA content in marasmic children.消瘦儿童脑重量、胆固醇、磷脂及DNA含量的变化
Am J Clin Nutr. 1970 Oct;23(10):1275-9. doi: 10.1093/ajcn/23.10.1275.

脑重量与肝脏重量比值增加作为宫内营养不良的尸检征象。

Increased brain weight-liver weight ratio as a necropsy sign of intrauterine undernutrition.

作者信息

Anderson J M

出版信息

J Clin Pathol. 1972 Oct;25(10):867-71. doi: 10.1136/jcp.25.10.867.

DOI:10.1136/jcp.25.10.867
PMID:4646298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC477537/
Abstract

Comparison of the brain weight/liver weight ratio(1) with the body weight of 95 stillborn and neonatally deceased infants of gestation 25-42 weeks shows that in appropriately grown infants the mean value ratio is 2.8 and is unchanged with increasing maturity. The normal range is 1.7-4.1. Survival time has no significant effect on the ratio as studied in this necropsy population. Dysmature infants of body weight less than 1 SD below the mean body weight for gestation are characterized by a brain: liver weight ratio of 4.5 or more. On the basis of these observations the brain: liver weight ratio may be employed as a guide to the prenatal nutrition of infants at necropsy.

摘要

对95例孕25 - 42周死产及新生儿期死亡婴儿的脑重/肝重比(1)与体重进行比较,结果显示,在发育正常的婴儿中,该比值的平均值为2.8,且不随成熟度增加而变化。正常范围为1.7 - 4.1。在该尸检人群中研究发现,存活时间对该比值无显著影响。体重低于同孕周平均体重1个标准差的发育不成熟婴儿,其脑:肝重比为4.5或更高。基于这些观察结果,脑:肝重比可作为尸检时评估婴儿产前营养状况的一项指标。