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一种用于替换肱骨近端的生物陶瓷假体。

A bioceramic endoprosthesis for the replacement of the proximal humerus.

作者信息

Salzer M, Knahr K, Locke H, Stärk N, Matejovsky Z, Plenk H, Punzet G, Zweymüller K

出版信息

Arch Orthop Trauma Surg (1978). 1979 Mar 19;93(3):169-84. doi: 10.1007/BF00523668.

Abstract

In patients with malignant tumors in the region of the shoulder, radical resection can avoid amputation in most instances. To improve the function of the arm, endoprosthetic replacement of the defect is desirable. A three-component endoprosthesis made of a bioceramic material (aluminium oxide) was designed, implanted without bone cement. Fast anchorage to bone is achieved by using a conical sleeve, fixed upon the previously conically reamed humerus shaft. A stable primary fit is always feasible. Subsequent bone in growth into grooves inside the conical sleeve provides a permanent anchorage of the endoprosthesis. The authors experiences are based on implantations of 38 endoprostheses. The original diseases were primary malignant bone tumors in 19 patients, one case of "solitary" plasmocytoma and metastases into the proximal humerus in 16 patients. In two women, resection was made because of posttraumatic subcapital humeral pseudarthrosis. The follow-up study includes only those 27 cases operated on at least one year ago. 12 of the 14 patients with primary tumors have been surviving for 12-55 months (range 27.4) without signs of metastases or recurrent disease. Seven patients with metastases died of their original diseases after 7.7 months on the average. Owing to extensive resection of the shoulder musculature the mobility in the shoulder joint is considerably reduced. All the patients have good movement of the elbow joint and free function of the hand.

摘要

对于肩部区域患有恶性肿瘤的患者,根治性切除在大多数情况下可避免截肢。为改善手臂功能,缺损部位采用内置假体置换是可取的。设计了一种由生物陶瓷材料(氧化铝)制成的三分体假体,无需骨水泥植入。通过使用一个圆锥形套筒实现快速骨锚固,该套筒固定在先前经圆锥形扩髓的肱骨干上。始终能够实现稳定的初始贴合。随后骨长入圆锥形套筒内部的凹槽中,为假体提供永久锚固。作者的经验基于38例假体植入。原发疾病为19例原发性恶性骨肿瘤、1例“孤立性”浆细胞瘤以及16例肱骨近端转移瘤。两名女性因创伤后肱骨头下假关节进行了切除。随访研究仅包括至少一年前接受手术的27例病例。14例原发性肿瘤患者中有12例已存活12至55个月(平均27.4个月),无转移或疾病复发迹象。7例转移瘤患者平均7.7个月后死于原发病。由于肩部肌肉组织的广泛切除,肩关节活动度明显降低。所有患者肘关节活动良好,手部功能正常。

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